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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

12,401–12,450 of 18,558 reactions from Rhea

cycloheximide(in) + ATP + H2O = cycloheximide(out) + ADP + phosphate + H(+)
Direction not assertedBalancedTransportRhea 61936
3beta-hydroxy-16alpha,17alpha-epoxypregnenolone + UDP-alpha-D-glucose = 3beta-hydroxy-16alpha,17alpha-epoxypregnenolone 3-beta-D-glucoside + UDP + H(+)
Direction not assertedBalancedRhea 61940
24-methylenecholesterol + UDP-alpha-D-glucose = 24-methylene cholesteryl beta-D-glucoside + UDP + H(+)
Direction not assertedBalancedRhea 61944
N(6),N(6)-dimethyl-L-lysyl-[protein] + 2-oxoglutarate + O2 = N(6)-methyl-L-lysyl-[protein] + formaldehyde + succinate + CO2
Direction not assertedBalance undeterminableRhea 61948
N(6),N(6),N(6)-trimethyl-L-lysyl-[protein] + 2-oxoglutarate + O2 = N(6),N(6)-dimethyl-L-lysyl-[protein] + formaldehyde + succinate + CO2
Direction not assertedBalance undeterminableRhea 61952
1-O-octadecyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = 1-(1Z-octadecenyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O

Direction not assertedBalance undeterminableRhea 61956

a 1-O-hexadecyl-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = a 1-O-(1Z-hexadecenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O

Left to rightBalance undeterminableRhea 61960

a 1-O-octadecyl-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = a 1-O-(1Z-octadecenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O

Left to rightBalance undeterminableRhea 61964

a 1-O-(9Z-octadecenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = a 1-O-(1Z,9Z-octadecadienyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O

Left to rightBalance undeterminableRhea 61968

1-O-(13-methyltetradecyl)-2-(13-methyltetradecanoyl)-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = 1-O-(1Z-13-methyltetradecenyl)-2-(13-methyltetradecanoyl)-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O

Direction not assertedBalance undeterminableRhea 61972

glycyl-[protein] + reduced [flavodoxin] + S-adenosyl-L-methionine = glycin-2-yl radical-[protein] + semiquinone [flavodoxin] + 5'-deoxyadenosine + L-methionine + H(+)

Direction not assertedBalance undeterminableRhea 61976

ubiquinone-10 + NADPH + H(+) = ubiquinol-10 + NADP(+)

Left to rightBalancedRhea 61980

ubiquinone-10 + NADH + H(+) = ubiquinol-10 + NAD(+)

Left to rightBalancedRhea 61984

cytidine(72) in tRNA + S-adenosyl-L-methionine = 5-methylcytidine(72) in tRNA + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 61988

N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+)

Left to rightBalance undeterminableRhea 61992

(S)-lactoyl-CoA + L-lysyl-[protein] = N(6)-[(S)-lactoyl]-L-lysyl-[protein] + CoA + H(+)

Left to rightBalance undeterminableRhea 61996

protoporphyrinogen IX + 3 A = protoporphyrin IX + 3 AH2

Direction not assertedBalancedRhea 62000

an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc6S derivative + GDP-beta-L-fucose = an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc6S derivative + GDP + H(+)

Left to rightBalance undeterminableRhea 62004

alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc + GDP-beta-L-fucose = alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc + GDP + H(+)

Left to rightBalancedRhea 62008

cytidine(2499) in 23S rRNA + S-adenosyl-L-methionine = 5-methylcytidine(2499) in 23S rRNA + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 62012

L-seryl-[EGF-like domain protein] + UDP-alpha-D-xylose = 3-O-(beta-D-xylosyl)-L-seryl-[EGF-like domain protein] + UDP + H(+)

Direction not assertedBalance undeterminableRhea 62016

sitosteryl 3-beta-D-glucoside + H2O = sitosterol + D-glucose

Direction not assertedBalancedRhea 62020

campesteryl 3-beta-D-glucoside + H2O = campesterol + D-glucose

Direction not assertedBalancedRhea 62024

stigmasteryl 3-beta-D-glucoside + H2O = stigmasterol + D-glucose

Left to rightBalancedRhea 62028

a 1,2-diacyl-sn-glycero-3-phosphoglycerol + H2O = a 2-acyl-sn-glycero-3-phosphoglycerol + a fatty acid + H(+)

Direction not assertedBalance undeterminableRhea 62032

a 1-(9Z-octadecenoyl)-2-acyl-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + a fatty acid + H(+)

Direction not assertedBalance undeterminableRhea 62036

N-(octanoyl)-sphing-4-enine-1-phosphate + H2O = N-octanoylsphing-4-enine + phosphate

Left to rightBalancedRhea 62040

a 1-(9Z-octadecenoyl)-2-acyl-sn-glycero-3-phosphoglycerol + H2O = a 2-acyl-sn-glycero-3-phosphoglycerol + (9Z)-octadecenoate + H(+)

Direction not assertedBalance undeterminableRhea 62044

an N-aryl-1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine + H2O = an N-aryl-1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + hexadecanoate + H(+)

Direction not assertedBalance undeterminableRhea 62048

a 1-(9Z-octadecenoyl)-2-acyl-sn-glycero-3-phosphate + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + a fatty acid + H(+)

Direction not assertedBalance undeterminableRhea 62052

alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc + GDP-beta-L-fucose = alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc + GDP + H(+)

Left to rightBalancedRhea 62056

alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc + GDP-beta-L-fucose = alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc + GDP + H(+)

Left to rightBalancedRhea 62060

2-deoxy-D-glucose 6-phosphate + NAD(+) = 2-deoxy-6-phospho-D-glucono-1,5-lactone + NADH + H(+)

Left to rightBalancedRhea 62064

2-deoxy-D-glucose 6-phosphate + NADP(+) = 2-deoxy-6-phospho-D-glucono-1,5-lactone + NADPH + H(+)

Left to rightBalancedRhea 62068

D-galactose 6-phosphate + NADP(+) = 6-phospho-D-galactono-1,5-lactone + NADPH + H(+)

Left to rightBalancedRhea 62072

D-galactose 6-phosphate + NAD(+) = 6-phospho-D-galactono-1,5-lactone + NADH + H(+)

Left to rightBalancedRhea 62076

D-glucose 6-sulfate + NADP(+) = 6-sulfo-D-glucono-1,5-lactone + NADPH + H(+)

Left to rightBalancedRhea 62080

D-glucosamine + ADP = D-glucosamine 6-phosphate + AMP + H(+)

Direction not assertedBalancedRhea 62084

D-glucosamine 6-phosphate + NADP(+) = 2-amino-2-deoxy-6-phospho-D-glucono-1,5-lactone + NADPH + 2 H(+)

Left to rightBalancedRhea 62088

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-diphosphate + H2O = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + phosphate + H(+)

Direction not assertedBalancedRhea 62092

2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O = 2-(9Z-octadecenoyl)-glycerol + phosphate

Direction not assertedBalancedRhea 62096

1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + hexadecanoate + H(+)

Direction not assertedBalancedRhea 62100

sn-glycero-3-phosphoethanolamine + (9Z)-octadecenoyl-CoA = (9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA

Direction not assertedBalancedRhea 62104

sn-glycero-3-phosphoethanolamine + an acyl-CoA = a monoacyl-sn-glycero-3-phosphoethanolamine + CoA

Direction not assertedBalance undeterminableRhea 62108

(3S)-3-hydroxy-D-aspartate = iminosuccinate + H2O

Direction not assertedBalancedRhea 62112

iminosuccinate + H2O = oxaloacetate + NH4(+)

Direction not assertedBalancedRhea 62116

5-hydroxymethyl-dCMP + ATP = 5-hydroxymethyl-dCDP + ADP

Direction not assertedBalancedRhea 62120

a 2'-deoxyribonucleoside 5'-phosphate + GTP = a 2'-deoxyribonucleoside 5'-diphosphate + GDP

Direction not assertedBalance undeterminableRhea 62124

a 2'-deoxyribonucleoside 5'-phosphate + dGTP = a 2'-deoxyribonucleoside 5'-diphosphate + dGDP

Direction not assertedBalance undeterminableRhea 62128

a 2'-deoxyribonucleoside 5'-phosphate + dTTP = a 2'-deoxyribonucleoside 5'-diphosphate + dTDP

Direction not assertedBalance undeterminableRhea 62132

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