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12,301–12,350 of 12,877 reactions from Human-GEM
lactone form of nifedipine[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR12690
Nitropyridine metabolite of nifedipine[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR12691
hydroxy metabolite of nifedipine[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR12692
oxypurinol[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR12693
oxypurinol-1-riboside[e] =
oxypurinol-7-riboside[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR12695
des-isoproylpropionic-acid-fluvastatin[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR12696
pitavastatin[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR12697
pitavastatin-lactone[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR12698
pitavastatin-M3[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR12699
pravastatin[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR12700
pravastatin glucuronide[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR12701
rosuvastatin[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR12702
rosuvastatin-5S-lactone[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR12703
sulphate-conjugate-3-methoxy-acetaminophen[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR12704
simvastatin lactone form[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR12705
simvastatin dihydroxy acid form[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR12706
sulphate-conjugate of thiomethyl-acetaminophen[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR12707
sulphate-conjugate-acetaminophen[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR12708
Tacrolimus[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR12709
taurine conjugate of S-ibuprofen[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR12710
threo-isomer of fluvastain[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR12711
trans-lactone-fluvastatin[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR12712
Torasemide[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR12713
Torasemide-M1[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR12714
Torasemide-M3[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR12715
Torasemide-M5[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR12716
triol metabolite of pravastatin[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR12717
thiomethyl-sulphoxide-acetaminophen-glucuronide[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR12718
thiomethyl-sulphoxide-acetaminophen-sulphate[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR12719
UDP-glucuronate[r] + fluvastatin[r] = H+[r] + UDP[r] + fluvstatin-glucuronide[r]
Left to rightBalancedDrug metabolismHuman-GEM MAR12720
UDP-glucuronate[r] + des-isopropyl-dihydro-fluvastatin-tetranor[r] = H+[r] + UDP[r] + des-isopropyl-dihydro-fluvastatin-tetranor-glucuronide[r]
Left to rightBalancedDrug metabolismHuman-GEM MAR12721
des-isopropyl-dihydro-fluvastatin-tetranor-glucuronide[c] = des-isopropyl-dihydro-fluvastatin-tetranor-glucuronide[e]
ReversibleBalancedTransportDrug metabolismHuman-GEM MAR12722
des-isopropyl-dihydro-fluvastatin-tetranor[c] = des-isopropyl-dihydro-fluvastatin-tetranor[e]
ReversibleBalancedTransportDrug metabolismHuman-GEM MAR12723
H2O[r] + trans-lactone-fluvastatin[r] = fluvastatin[r]
Left to rightBalancedDrug metabolismHuman-GEM MAR12724
ATP[c] + H2O[c] + fluvastatin[c] = ADP[c] + H+[c] + Pi[c] + fluvastatin[e]
Left to rightBalancedTransportDrug metabolismHuman-GEM MAR12725
fluvastatin[c] = fluvastatin[e]
ReversibleBalancedTransportDrug metabolismHuman-GEM MAR12726
HCO3-[c] + fluvastatin[e] = HCO3-[e] + fluvastatin[c]
ReversibleBalancedTransportDrug metabolismHuman-GEM MAR12727
SAH[r] + UDP-glucuronate[r] + 3-methoxy-acetaminophen[r] = SAM[r] + UDP[r] + glucuronide-conjugate of 3-methoxy-acetaminophen[r]
Left to rightBalancedEC 2.4.1.17Drug metabolismHuman-GEM MAR12728
ATP[c] + H2O[c] + glucuronide-conjugate of 3-methoxy-acetaminophen[c] = ADP[c] + H+[c] + Pi[c] + glucuronide-conjugate of 3-methoxy-acetaminophen[e]
Left to rightBalancedTransportDrug metabolismHuman-GEM MAR12729
ATP[c] + H2O[c] + Gliclazide[c] = ADP[c] + H+[c] + Pi[c] + Gliclazide[e]
Left to rightBalancedTransportDrug metabolismHuman-GEM MAR12730
Gliclazide[e] = Gliclazide[c]
ReversibleBalancedTransportDrug metabolismHuman-GEM MAR12731
UDP-glucuronate[r] + thiomethyl-conjugate-acetaminophen[r] = H+[r] + UDP[r] + glucuronide-thiomethyl-acetaminophen conjugate[r]
Left to rightBalancedDrug metabolismHuman-GEM MAR12732
ATP[c] + H2O[c] + glucuronide-thiomethyl-acetaminophen conjugate[c] = ADP[c] + H+[c] + Pi[c] + glucuronide-thiomethyl-acetaminophen conjugate[e]
Left to rightBalancedTransportDrug metabolismHuman-GEM MAR12733
ibuprofen acyl glucuronide[e] = ibuprofen acyl glucuronide[c]
ReversibleBalancedTransportDrug metabolismHuman-GEM MAR12734
ATP[c] + H2O[c] + ibuprofen acyl glucuronide[c] = ADP[c] + H+[c] + Pi[c] + ibuprofen acyl glucuronide[e]
Left to rightBalancedTransportDrug metabolismHuman-GEM MAR12735
UDP-glucuronate[r] + ibuprofen-S[r] = UDP[r] + ibuprofen acyl glucuronide[r]
Left to rightBalancedEC 2.4.1.17Drug metabolismHuman-GEM MAR12736
ATP[c] + CoA[c] + ibuprofen-R[c] = AMP[c] + PPi[c] + ibuprofen-CoA-R form[c]
Left to rightBalancedEC 6.2.1.3Drug metabolismHuman-GEM MAR12737
H+[r] + NADPH[r] + O2[r] + ibuprofen-R[r] = H2O[r] + NADP+[r] + 2-hydroxy-R-ibuprofen[r]
Left to rightBalancedEC 1.14.13.-, 1.14.14.1Drug metabolismHuman-GEM MAR12738
H+[r] + NADPH[r] + O2[r] + ibuprofen-R[r] = H2O[r] + NADP+[r] + 3-hydroxy R-ibuprofen[r]
Left to rightBalancedEC 1.14.13.-, 1.14.14.1Drug metabolismHuman-GEM MAR12739