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11,751–11,800 of 12,877 reactions from Human-GEM
0.0031466 1,2-diacylglycerol-LD-TAG pool[c] + 0.0012642 2-lysolecithin pool[c] + 0.11871 alanine[c] + 0.0009274 arginine[c] + 0.012056 asparagine[c] + 0.69277 aspartate[c] + 0.0082708 cholesterol[c] + 0.0065713 cholesterol-ester pool[r] + 0.00057356 CL pool[c] + 0.001 cofactors and vitamins[c] + 0.0012056 cysteine[c] + 0.007581 DNA[n] + 0.16786 glutamate[c] + 0.19104 glutamine[c] + 0.13911 glycine[c] + 0.028749 histidine[c] + 0.0037096 isoleucine[c] + 0.011129 leucine[c] + 0.009274 lysine[c] + 0.0018548 methionine[c] + 0.017171 PC-LD pool[c] + 0.020051 PE-LD pool[c] + 0.0037096 phenylalanine[c] + 0.016414 phosphatidate-LD-TAG pool[c] + 0.0030972 PI pool[c] + 0.017992 proline[c] + 0.005891 PS-LD pool[c] + 0.0308145 RNA[c] + 0.037096 serine[c] + 0.0024143 SM pool[c] + 0.027482 TAG-LD pool[c] + 0.020403 threonine[c] + 0.0009274 tryptophan[c] + 0.0055644 tyrosine[c] + 0.012056 valine[c] + 0.26551 glycogen[c] + 0.0038601 1-acylglycerol-3P pool[c] = biomass[c]
BlockedBalance undeterminableEC 2.5.1.18Artificial reactionsHuman-GEM MAR12140
NADH[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR12141
12-dehydrocholic acid[c] + ATP[c] + H2O[c] = 12-dehydrocholic acid[e] + ADP[c] + H+[c] + Pi[c]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR12142
12-dehydrocholic acid[e] + HCO3-[c] = 12-dehydrocholic acid[c] + HCO3-[e]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR12143
12-dehydrocholic acid[e] + 2 Na+[e] = 12-dehydrocholic acid[c] + 2 Na+[c]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR12144
cholate[c] + H+[c] + NADPH[c] + O2[c] = 2 H2O[c] + NADP+[c] + 3-dehydrocholic acid[c]
Left to rightBalancedEC 1.14.14.57Bile acid biosynthesisHuman-GEM MAR12145
chenodiol[c] + H+[c] + NADPH[c] + O2[c] = 2 H2O[c] + NADP+[c] + 3-dehydrochenodeoxycholic acid[c]
Left to rightBalancedEC 1.14.14.57Bile acid biosynthesisHuman-GEM MAR12146
ATP[c] + H2O[c] + 3-dehydrochenodeoxycholic acid[c] = ADP[c] + H+[c] + Pi[c] + 3-dehydrochenodeoxycholic acid[e]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR12147
HCO3-[c] + 3-dehydrochenodeoxycholic acid[e] = HCO3-[e] + 3-dehydrochenodeoxycholic acid[c]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR12148
2 Na+[e] + 3-dehydrochenodeoxycholic acid[e] = 2 Na+[c] + 3-dehydrochenodeoxycholic acid[c]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR12149
ATP[c] + H2O[c] + 3-dehydrocholic acid[c] = ADP[c] + H+[c] + Pi[c] + 3-dehydrocholic acid[e]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR12150
HCO3-[c] + 3-dehydrocholic acid[e] = HCO3-[e] + 3-dehydrocholic acid[c]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR12151
2 Na+[e] + 3-dehydrocholic acid[e] = 2 Na+[c] + 3-dehydrocholic acid[c]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR12152
ATP[c] + H2O[c] + 3-dehydro-Deoxycholate[c] = ADP[c] + H+[c] + Pi[c] + 3-dehydro-Deoxycholate[e]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR12153
3alpha,12alpha-dihydroxy-5beta-cholanate[c] + H+[c] + NADPH[c] + O2[c] = 2 H2O[c] + NADP+[c] + 3-dehydro-Deoxycholate[c]
Left to rightBalancedEC 1.14.14.57Bile acid biosynthesisHuman-GEM MAR12154
HCO3-[c] + 3-dehydro-Deoxycholate[e] = HCO3-[e] + 3-dehydro-Deoxycholate[c]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR12155
2 Na+[e] + 3-dehydro-Deoxycholate[e] = 2 Na+[c] + 3-dehydro-Deoxycholate[c]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR12156
ATP[c] + H2O[c] + 3-dehydro-Lithocholate[c] = ADP[c] + H+[c] + Pi[c] + 3-dehydro-Lithocholate[e]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR12157
H+[c] + lithocholate[c] + NADPH[c] + O2[c] = 2 H2O[c] + NADP+[c] + 3-dehydro-Lithocholate[c]
Left to rightBalancedEC 1.14.14.57Bile acid biosynthesisHuman-GEM MAR12158
HCO3-[c] + 3-dehydro-Lithocholate[e] = HCO3-[e] + 3-dehydro-Lithocholate[c]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR12159
2 Na+[e] + 3-dehydro-Lithocholate[e] = 2 Na+[c] + 3-dehydro-Lithocholate[c]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR12160
ATP[c] + H2O[c] + 7-dehydrochenodeoxycholic acid[c] = ADP[c] + H+[c] + Pi[c] + 7-dehydrochenodeoxycholic acid[e]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR12161
HCO3-[c] + 7-dehydrochenodeoxycholic acid[e] = HCO3-[e] + 7-dehydrochenodeoxycholic acid[c]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR12162
2 Na+[e] + 7-dehydrochenodeoxycholic acid[e] = 2 Na+[c] + 7-dehydrochenodeoxycholic acid[c]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR12163
ATP[c] + H2O[c] + 7-dehydrocholic acid[c] = ADP[c] + H+[c] + Pi[c] + 7-dehydrocholic acid[e]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR12164
HCO3-[c] + 7-dehydrocholic acid[e] = HCO3-[e] + 7-dehydrocholic acid[c]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR12165
2 Na+[e] + 7-dehydrocholic acid[e] = 2 Na+[c] + 7-dehydrocholic acid[c]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR12166
cholate[c] + UDP-glucuronate[c] = UDP[c] + Cholic acid-24glucuronide, CA-24G[c]
Left to rightBalancedEC 2.4.1.17Bile acid biosynthesisHuman-GEM MAR12167
cholate[r] + UDP-glucuronate[r] = UDP[r] + Cholic acid-24glucuronide, CA-24G[r]
Left to rightBalancedEC 2.4.1.17Bile acid biosynthesisHuman-GEM MAR12168
ATP[c] + H2O[c] + Cholic acid-24glucuronide, CA-24G[c] = ADP[c] + H+[c] + Pi[c] + Cholic acid-24glucuronide, CA-24G[e]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR12169
Cholic acid-24glucuronide, CA-24G[c] = Cholic acid-24glucuronide, CA-24G[r]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR12170
ATP[c] + H2O[c] + Cholic acid 3-sulfate[c] = ADP[c] + H+[c] + Pi[c] + Cholic acid 3-sulfate[e]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR12171
HCO3-[c] + Cholic acid 3-sulfate[e] = HCO3-[e] + Cholic acid 3-sulfate[c]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR12172
cholate[c] + PAPS[c] = H+[c] + PAP[c] + Cholic acid 3-sulfate[c]
Left to rightBalancedEC 2.8.2.14Bile acid biosynthesisHuman-GEM MAR12173
chenodiol[c] + UDP-glucuronate[c] = UDP[c] + Chenodeoxycholic acid-24glucuronide, CDCA-24G[c]
Left to rightBalancedEC 2.4.1.17Bile acid biosynthesisHuman-GEM MAR12174
chenodiol[r] + UDP-glucuronate[r] = UDP[r] + Chenodeoxycholic acid-24glucuronide, CDCA-24G[r]
Left to rightBalancedEC 2.4.1.17Bile acid biosynthesisHuman-GEM MAR12175
ATP[c] + H2O[c] + Chenodeoxycholic acid-24glucuronide, CDCA-24G[c] = ADP[c] + H+[c] + Pi[c] + Chenodeoxycholic acid-24glucuronide, CDCA-24G[e]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR12176
Chenodeoxycholic acid-24glucuronide, CDCA-24G[c] = Chenodeoxycholic acid-24glucuronide, CDCA-24G[r]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR12177
chenodiol[c] + UDP-glucuronate[c] = UDP[c] + Chenodeoxycholic acid-3glucuronide, CDCA-3G[c]
Left to rightBalancedEC 2.4.1.17Bile acid biosynthesisHuman-GEM MAR12178
chenodiol[r] + UDP-glucuronate[r] = UDP[r] + Chenodeoxycholic acid-3glucuronide, CDCA-3G[r]
Left to rightBalancedEC 2.4.1.17Bile acid biosynthesisHuman-GEM MAR12179
ATP[c] + H2O[c] + Chenodeoxycholic acid-3glucuronide, CDCA-3G[c] = ADP[c] + H+[c] + Pi[c] + Chenodeoxycholic acid-3glucuronide, CDCA-3G[e]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR12180
Chenodeoxycholic acid-3glucuronide, CDCA-3G[c] = Chenodeoxycholic acid-3glucuronide, CDCA-3G[r]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR12181
HCO3-[c] + sulfochenodeoxycholate[e] = HCO3-[e] + sulfochenodeoxycholate[c]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR12182
chenodiol[c] + H+[c] + NADPH[c] + O2[c] = H2O[c] + NADP+[c] + hyocholic acid[c]
Left to rightBalancedEC 1.14.14.57Bile acid biosynthesisHuman-GEM MAR12183
ATP[c] + H2O[c] + Coprostanol[c] = ADP[c] + H+[c] + Pi[c] + Coprostanol[e]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR12184
HCO3-[c] + Coprostanol[e] = HCO3-[e] + Coprostanol[c]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR12185
2 Na+[e] + Coprostanol[e] = 2 Na+[c] + Coprostanol[c]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR12186
3alpha,12alpha-dihydroxy-5beta-cholanate[c] + UDP-glucuronate[c] = UDP[c] + Deoxycholic acid-24glucuronide, CDA-24G[c]
Left to rightBalancedEC 2.4.1.17Bile acid biosynthesisHuman-GEM MAR12187
3alpha,12alpha-dihydroxy-5beta-cholanate[r] + UDP-glucuronate[r] = UDP[r] + Deoxycholic acid-24glucuronide, CDA-24G[r]
Left to rightBalancedEC 2.4.1.17Bile acid biosynthesisHuman-GEM MAR12188
ATP[c] + H2O[c] + Deoxycholic acid-24glucuronide, CDA-24G[c] = ADP[c] + H+[c] + Pi[c] + Deoxycholic acid-24glucuronide, CDA-24G[e]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR12189