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9,701–9,750 of 12,877 reactions from Human-GEM
fatty acid-chylomicron pool[c] = fatty acid-chylomicron pool[e]
Left to rightBalance undeterminableTransportTransport reactionsHuman-GEM MAR10050
fatty acid-VLDL pool[c] = fatty acid-VLDL pool[e]
Left to rightBalance undeterminableTransportTransport reactionsHuman-GEM MAR10051
phosphatidate-LD-PC pool[c] = phosphatidate-LD-PC pool[m]
ReversibleBalance undeterminableTransportTransport reactionsHuman-GEM MAR10052
phosphatidate-LD-PI pool[c] = phosphatidate-LD-PI pool[m]
ReversibleBalance undeterminableTransportTransport reactionsHuman-GEM MAR10053
phosphatidate-LD-PI pool[c] = phosphatidate-LD-PI pool[r]
ReversibleBalance undeterminableTransportTransport reactionsHuman-GEM MAR10054
phosphatidate-LD-PI pool[c] = phosphatidate-LD-PI pool[g]
ReversibleBalance undeterminableTransportTransport reactionsHuman-GEM MAR10055
phosphatidate-LD-PS pool[c] = phosphatidate-LD-PS pool[r]
ReversibleBalance undeterminableTransportTransport reactionsHuman-GEM MAR10056
phosphatidate-LD-PS pool[c] = phosphatidate-LD-PS pool[g]
ReversibleBalance undeterminableTransportTransport reactionsHuman-GEM MAR10057
[protein][c] = [protein][r]
ReversibleBalance undeterminableTransportTransport reactionsHuman-GEM MAR10058
N-formyl-L-glutamate[c] = N-formyl-L-glutamate[e]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR10059
N-formyl-L-glutamate[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR10060
2 H+[x] + 2 NADPH[x] + acyl-CoA pool[x] = CoA[x] + 2 NADP+[x] + Hydroxy Alkyl Chain[x]
Left to rightBalance undeterminableEC 1.2.1.84Ether lipid metabolismHuman-GEM MAR10061
0.0721 glycyl-tRNA(gly)[c] + 0.0801 L-alanyl-tRNA(ala)[c] + 0.0512 L-arginyl-tRNA(arg)[c] + 0.0375 L-asparaginyl-tRNA(asn)[c] + 0.0556 L-aspartyl-tRNA(asp)[c] + 0.0183 L-cysteinyl-tRNA(cys)[c] + 0.0428 L-glutaminyl-tRNA(gln)[c] + 0.0783 L-glutamyl-tRNA(glu)[c] + 0.0228 L-histidyl-tRNA(his)[c] + 0.0442 L-isoleucyl-tRNA(ile)[c] + 0.0911 L-leucyl-tRNA(leu)[c] + 0.0719 L-lysyl-tRNA(lys)[c] + 0.0222 L-methionyl-tRNA(met)[c] + 0.0368 L-phenylalanyl-tRNA(phe)[c] + 0.051 L-prolyl-tRNA(pro)[c] + 0.0661 L-seryl-tRNA(ser)[c] + 0.0535 L-threonyl-tRNA(thr)[c] + 0.0098 L-tryptophanyl-tRNA(trp)[c] + 0.0281 L-tyrosyl-tRNA(tyr)[c] + 0.0667 L-valyl-tRNA(val)[c] = 0.0801 tRNA(ala)[c] + 0.0512 tRNA(arg)[c] + 0.0375 tRNA(asn)[c] + 0.0556 tRNA(asp)[c] + 0.0183 tRNA(cys)[c] + 0.0428 tRNA(gln)[c] + 0.0783 tRNA(glu)[c] + 0.0721 tRNA(gly)[c] + 0.0228 tRNA(his)[c] + 0.0442 tRNA(ile)[c] + 0.0911 tRNA(leu)[c] + 0.0719 tRNA(lys)[c] + 0.0222 tRNA(met)[c] + 0.0368 tRNA(phe)[c] + 0.051 tRNA(pro)[c] + 0.0661 tRNA(ser)[c] + 0.0535 tRNA(thr)[c] + 0.0098 tRNA(trp)[c] + 0.0281 tRNA(tyr)[c] + 0.0667 tRNA(val)[c] + protein_pool_biomass[c]
Left to rightBalance undeterminableArtificial reactionsHuman-GEM MAR10062
0.1155 cholesterol[c] + 0.0115 cholesterol-ester pool[c] + 0.0205 CL pool[c] + 0.5029 PC-LD pool[c] + 0.1905 PE-LD pool[c] + 0.0096 PG-CL pool[c] + 0.0692 PI pool[c] + 0.019 PS-LD pool[c] + 0.0613 SM pool[c] = lipid_pool_biomass[c]
Left to rightBalance undeterminableArtificial reactionsHuman-GEM MAR10063
0.0043 (S)-dihydroorotate[c] + 0.0014 2,3-bisphospho-D-glycerate[c] + 0.0022 3-phospho-D-glycerate[c] + 0.0025 3-phosphoserine[c] + 0.0002 acetyl-CoA[c] + 0.0033 ADP[c] + 0.0046 AKG[c] + 0.0404 alanine[c] + 0.0002 AMP[c] + 0.0015 arginine[c] + 0.0012 asparagine[c] + 0.0865 aspartate[c] + 0.0271 ATP[c] + 0.0034 citrate[c] + 0.0234 CoA[c] + 0.0052 CTP[c] + 0.0005 cysteine[c] + 0.0001 dAMP[c] + 0.0002 dCMP[c] + 0.0094 DHAP[c] + 0.0088 fructose-1,6-bisphosphate[c] + 0.0006 fructose-6-phosphate[c] + 0.0028 fumarate[c] + 0.0008 D-glyceraldehyde 3-phosphate[c] + 0.0002 GDP[c] + 0.0039 glucose-6-phosphate[c] + 0.3694 glutamate[c] + 0.0998 glutamine[c] + 0.0215 glycine[c] + 0.0001 GMP[c] + 0.0179 GSH[c] + 0.0001 GSSG[c] + 0.0039 GTP[c] + 0.0024 histidine[c] + 0.0002 isocitrate[c] + 0.0102 isoleucine[c] + 0.0102 leucine[c] + 0.0029 lysine[c] + 0.0081 malate[c] + 0.0037 methionine[c] + 0.0029 NAD+[c] + 0.0004 NADH[c] + 0.0002 NADP+[c] + 0.0004 NADPH[c] + 0.0049 phenylalanine[c] + 0.0102 phenylpyruvate[c] + 0.0071 proline[c] + 0.034 pyruvate[c] + 0.0002 ribose-5-phosphate[c] + 0.0282 serine[c] + 0.0388 threonine[c] + 0.001 tryptophan[c] + 0.0054 tyrosine[c] + 0.0008 UDP[c] + 0.0088 UDP-glucose[c] + 0.0006 UDP-glucuronate[c] + 0.052 UDP-N-acetylglucosamine[c] + 0.0102 UTP[c] + 0.0088 valine[c] = metabolite_pool_biomass[c]
Left to rightBalance undeterminableArtificial reactionsHuman-GEM MAR10064
0.0345 11-cis-retinol[c] + 0.0172 18-hydroxy-all-trans-retinoate[c] + 0.0172 18-hydroxy-all-trans-retinoate[r] + 0.0172 24-oxo-1alpha,23,25-trihydroxyvitamin D3[c] + 0.0172 24-oxo-1alpha,23,25-trihydroxyvitamin D3[m] + 0.0172 25-hydroxyvitamin D3-26,23-lactone[c] + 0.0172 25-hydroxyvitamin D3-26,23-lactone[m] + 0.0345 3-carboxy-alpha-chromanol[c] + 0.0172 4-hydroxyvitamin A1[c] + 0.0172 4-hydroxyvitamin A1[r] + 0.0172 4-OH-13-cis-retinal[c] + 0.0172 4-OH-13-cis-retinal[r] + 0.0172 4-OH-retinal[c] + 0.0172 4-OH-retinal[r] + 0.0345 4-oxo-13-cis-retinoate[r] + 0.0172 4-oxo-9-cis-retinal[c] + 0.0172 4-oxo-9-cis-retinal[r] + 0.0172 4-oxo-9-cis-retinoyl-beta-glucuronide[c] + 0.0172 4-oxo-9-cis-retinoyl-beta-glucuronide[r] + 0.0172 4-oxo-all-trans-retinoate[c] + 0.0172 4-oxo-all-trans-retinoate[r] + 0.0345 4-oxoretinol[c] + 0.0345 5,8-epoxy-13-cis-retinoate[c] + 0.0345 9-cis-retinol[c] + 0.0345 biotin[c] + 0.0345 cobamide-coenzyme[m] + 0.0345 FADH2[c] + 0.0345 gamma-CEHC-glucuronide[c] + 0.0345 heme[m] + 0.0345 L-carnitine[c] + 0.0345 lipoic acid[c] + 0.0345 N-retinylidene-N-retinylethanolamine[c] + 0.0345 pyridoxal-phosphate[c] + 0.0345 riboflavin[c] + 0.0345 tetrahydrobiopterin[c] + 0.0345 THF[c] + 0.0345 thiamin-PP[c] + 0.0345 ubiquinol[m] = cofactor_pool_biomass[c]
Left to rightBalance undeterminableTransportArtificial reactionsHuman-GEM MAR10065
20alpha-hydroxy-4-pregnen-3-one[c] + NAD+[c] = H+[c] + NADH[c] + progesterone[c]
Left to rightBalancedEC 1.1.1.149Steroid metabolismHuman-GEM MAR10066
1D-myo-inositol-1,3,4,5,6-pentakisphosphate[c] + H2O[c] = 1D-myo-inositol-1,4,5,6-tetrakisphosphate[c] + Pi[c]
Left to rightBalancedEC 2.7.1.-Inositol phosphate metabolismHuman-GEM MAR10067
1D-myo-inositol-1,4,5,6-tetrakisphosphate[c] + H2O[c] = D-myo-inositol-1,4,5-trisphosphate[c] + Pi[c]
Left to rightBalancedInositol phosphate metabolismHuman-GEM MAR10068
deoxycholoyl-CoA[c] + glycine[c] = CoA[c] + glycodeoxycholate[c]
Left to rightBalancedBile acid biosynthesisHuman-GEM MAR10069
oxidized dithiothreitol[c] + 3-hydroxy-2-methyl-3-phytyl-2,3-dihydronaphthoquinone[c] = dithiothreitol[c] + 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone[c]
Left to rightBalancedMiscellaneousHuman-GEM MAR10070
NADP+[c] + 5alpha-Pregnan-20alpha-ol-3-one[c] = 5alpha-pregnane-3,20-dione[c] + H+[c] + NADPH[c]
Left to rightBalancedEC 1.1.1.-Steroid metabolismHuman-GEM MAR10071
NADP+[c] + 17alpha,20alpha-Dihydroxypregn-4-en-3-one[c] = 17alpha-hydroxyprogesterone[c] + H+[c] + NADPH[c]
Left to rightBalancedEC 1.1.1.-Steroid metabolismHuman-GEM MAR10072
ATP[c] + H2O[c] + alpha-muricholic acid[c] = ADP[c] + H+[c] + Pi[c] + alpha-muricholic acid[e]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR10073
alpha-muricholic acid[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR10074
ATP[c] + H2O[c] + beta-muricholic acid[c] = ADP[c] + H+[c] + Pi[c] + beta-muricholic acid[e]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR10075
beta-muricholic acid[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR10076
dehydrocholic acid[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR10077
tauro-alpha-muricholic acid[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR10078
ATP[c] + H2O[c] + tauro-alpha-muricholic acid[c] = ADP[c] + H+[c] + Pi[c] + tauro-alpha-muricholic acid[e]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR10079
ATP[c] + CoA[c] + alpha-muricholic acid[c] = AMP[c] + PPi[c] + alpha-muricholoyl-CoA[c]
Left to rightBalancedBile acid biosynthesisHuman-GEM MAR10080
omega-muricholic acid[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR10081
ATP[c] + H2O[c] + omega-muricholic acid[c] = ADP[c] + H+[c] + Pi[c] + omega-muricholic acid[e]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR10082
taurohyocholic acid[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR10083
glycohyocholic acid[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR10084
glycohyodeoxycholic acid[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR10085
glycodehydrocholic acid[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR10086
hyocholic acid[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR10087
tauro-omega-muricholic acid[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR10088
tauro-beta-muricholic acid[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR10089
murideoxycholic acid[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR10090
taurodehydrocholic acid[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR10091
H2O[c] + alpha-muricholoyl-CoA[c] = CoA[c] + H+[c] + alpha-muricholic acid[c]
Left to rightBalancedBile acid biosynthesisHuman-GEM MAR10092
taurine[c] + alpha-muricholoyl-CoA[c] = CoA[c] + H+[c] + tauro-alpha-muricholic acid[c]
Left to rightBalancedBile acid biosynthesisHuman-GEM MAR10093
ATP[c] + CoA[c] + beta-muricholic acid[c] = AMP[c] + PPi[c] + beta-muricholoyl-CoA[c]
Left to rightBalancedEC 6.2.1.7Bile acid biosynthesisHuman-GEM MAR10094
H2O[c] + beta-muricholoyl-CoA[c] = CoA[c] + H+[c] + beta-muricholic acid[c]
Left to rightBalancedBile acid biosynthesisHuman-GEM MAR10095
taurine[c] + beta-muricholoyl-CoA[c] = CoA[c] + H+[c] + tauro-beta-muricholic acid[c]
Left to rightBalancedBile acid biosynthesisHuman-GEM MAR10096
ATP[c] + CoA[c] + omega-muricholic acid[c] = AMP[c] + PPi[c] + omega-muricholoyl-CoA[c]
Left to rightBalancedEC 6.2.1.7Bile acid biosynthesisHuman-GEM MAR10097
H2O[c] + omega-muricholoyl-CoA[c] = CoA[c] + H+[c] + omega-muricholic acid[c]
Left to rightBalancedBile acid biosynthesisHuman-GEM MAR10098
taurine[c] + omega-muricholoyl-CoA[c] = CoA[c] + H+[c] + tauro-omega-muricholic acid[c]
Left to rightBalancedBile acid biosynthesisHuman-GEM MAR10099