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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
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PathwaysReactions grouped under one name
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Reference

Evidence

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

9,101–9,150 of 18,558 reactions from Rhea

a ganglioside GT1a + H2O = a ganglioside GD1a + N-acetylneuraminate
Direction not assertedBalance undeterminableRhea 48472
a ganglioside GT1a (d18:1(4E)) + H2O = a ganglioside GD1a (d18:1(4E)) + N-acetylneuraminate
Direction not assertedBalance undeterminableRhea 48476
1,2-di-(9Z-octadecenoyl)-sn-glycerol + UDP-alpha-D-galactose = 1,2-di-(9Z-octadecenoyl)-3-beta-D-galactosyl-sn-glycerol + UDP + H(+)
Direction not assertedBalancedRhea 48480
a propanoate ester + H2O = an aliphatic alcohol + propanoate + H(+)
Direction not assertedBalance undeterminableRhea 48484
all-trans-retinol--[retinol-binding protein] + NAD(+) = all-trans-retinal--[retinol-binding protein] + NADH + H(+)
Direction not assertedBalance undeterminableRhea 48488
1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycerol + UDP-alpha-D-galactose = 1,2-di-(9Z,12Z-octadecadienoyl)-3-beta-D-galactosyl-sn-glycerol + UDP + H(+)
Direction not asserted

Balanced

Rhea 48492

1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycerol + UDP-alpha-D-galactose = 1-(9Z-octadecenoyl)-2-hexadecanoyl-3-beta-D-galactosyl-sn-glycerol + UDP + H(+)

Direction not assertedBalancedRhea 48496

octanoylglycerol + H2O = octanoate + glycerol + H(+)

Direction not assertedBalancedRhea 48500

D-glycero-D-manno-heptose 1,7-bisphosphate + H2O = D-glycero-D-manno-heptose 1-phosphate + phosphate

Direction not assertedBalancedRhea 48504

cholate + NADP(+) = 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate + NADPH + H(+)

Direction not assertedBalancedRhea 48508

phosphinate(out) + ATP + H2O = phosphinate(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 48512

1,2-didodecanoyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H2O = dodecanoyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + dodecanoate + H(+)

Left to rightBalancedRhea 48516

[protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine methyl ester + H2O = [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine + methanol + H(+)

Direction not assertedBalance undeterminableRhea 48520

a ganglioside GP1c + H2O = a ganglioside GQ1c + N-acetylneuraminate

Direction not assertedBalance undeterminableRhea 48524

a ganglioside GP1c (d18:1(4E)) + H2O = a ganglioside GQ1c (d18:1(4E)) + N-acetylneuraminate

Direction not assertedBalance undeterminableRhea 48528

a ganglioside GQ1c (d18:1(4E)) + H2O = a ganglioside GT1c (d18:1(4E)) + N-acetylneuraminate

Direction not assertedBalance undeterminableRhea 48532

1-beta-D-galactosyl-2,3-didodecanoyl-sn-glycerol + H2O = 1-beta-D-galactosyl-dodecanoyl-sn-glycerol + dodecanoate + H(+)

Left to rightBalancedRhea 48536

1,2-didodecanoyl-3-beta-D-galactosyl-sn-glycerol + H2O = dodecanoyl-3-beta-D-galactosyl-sn-glycerol + dodecanoate + H(+)

Left to rightBalancedRhea 48540

[phosphatase 2A protein]-C-terminal L-leucine + S-adenosyl-L-methionine = [phosphatase 2A protein]-C-terminal L-leucine methyl ester + S-adenosyl-L-homocysteine

Direction not assertedBalance undeterminableRhea 48544

[phosphatase 2A protein]-C-terminal L-leucine methyl ester + H2O = [phosphatase 2A protein]-C-terminal L-leucine + methanol + H(+)

Direction not assertedBalance undeterminableRhea 48548

1-(9S,13S-12-oxo-10,15Z-phytodienoyl)-2-(7Z,10Z,13Z)-hexadecatrienoyl-3-O-(beta-D-galactosyl)-sn-glycerol + H2O = 2-(7Z,10Z,13Z)-hexadecatrienoyl-3-O-(beta-D-galactosyl)-sn-glycerol + (9S,13S,15Z)-12-oxophyto-10,15-dienoate + H(+)

Direction not assertedBalancedRhea 48552

5-phospho-alpha-D-ribose 1-diphosphate + 4-hydroxybenzoate + H(+) = 4-(beta-D-ribofuranosyl)phenol 5'-phosphate + CO2 + diphosphate

Direction not assertedBalancedRhea 48556

N(6)-(dimethylallyl)adenosine 5'-phosphate + H2O = N(6)-dimethylallyladenine + D-ribose 5-phosphate

Direction not assertedBalancedRhea 48560

9-ribosyl-trans-zeatin 5'-phosphate + H2O = trans-zeatin + D-ribose 5-phosphate

Direction not assertedBalancedRhea 48564

3-chlorocatechol + O2 = (2E,4Z)-2-chloromuconate + 2 H(+)

Direction not assertedBalancedRhea 48568

3,5-dichlorocatechol + O2 = (2E,4E)-2,4-dichloromuconate + 2 H(+)

Direction not assertedBalancedRhea 48572

4-chlorocatechol + O2 = 3-chloro-cis,cis-muconate + 2 H(+)

Direction not assertedBalancedRhea 48576

[pyruvate, water dikinase]-phosphate + phosphate + H(+) = [pyruvate, water dikinase] + diphosphate

Direction not assertedBalance undeterminableRhea 48580

2 leukotriene A4 + O2 + 2 H2O = 2 lipoxin A4

Left to rightBalancedRhea 48584

2 leukotriene A4 + O2 + 2 H2O = 2 lipoxin B4

Left to rightBalancedRhea 48588

a quinone + formate + H(+) = a quinol + CO2

Direction not assertedBalance undeterminableRhea 48592

1,2-didecanoylglycerol + H2O = decanoylglycerol + decanoate + H(+)

Left to rightBalancedRhea 48596

[protein-PII]-uridylyl-L-tyrosine + H2O = [protein-PII]-L-tyrosine + UMP + H(+)

Direction not assertedBalance undeterminableRhea 48600

2,3-dihydroxybenzoyl-5'-AMP + holo-[ACP] = 2,3-dihydroxybenzoyl-[ACP] + AMP + H(+)

Direction not assertedBalance undeterminableRhea 48604

a 2,3-saturated acyl-CoA + A = a 2,3-dehydroacyl-CoA + AH2

Direction not assertedBalance undeterminableRhea 48608

[molybdopterin-synthase sulfur-carrier protein]-C-terminal Gly-Gly-AMP + S-sulfanyl-L-cysteinyl-[cysteine desulfurase] + AH2 = [molybdopterin-synthase sulfur-carrier protein]-C-terminal-Gly-aminoethanethioate + L-cysteinyl-[cysteine desulfurase] + A + AMP + 2 H(+)

Direction not assertedBalance undeterminableRhea 48612

leukotriene D4 + H2O = leukotriene E4 + glycine

Left to rightBalancedRhea 48616

(5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + 2 glutathione = (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + glutathione disulfide + H2O

Left to rightBalancedRhea 48620

(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + O2 = (5S)-hydroperoxy-(15S)-hydroxy-(6E,8Z,11Z,13E)-eicosatetraenoate

Left to rightBalancedRhea 48624

a ribonucleotide in rRNA + S-adenosyl-L-methionine = a 2'-O-methylribonucleotide in rRNA + S-adenosyl-L-homocysteine + H(+)

Left to rightBalance undeterminableRhea 48628

(5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate = 5-oxo-(6E,8Z,11Z,14Z)-eicosatetraenoate + H2O

Left to rightBalancedRhea 48632

(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate = 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate + H2O

Left to rightBalancedRhea 48636

(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + NAD(+) = 11-oxo-(5Z,8Z,12E,14Z)-eicosatetraenoate + NADH + H(+)

Left to rightBalancedRhea 48640

prostaglandin H2 = (12S)-hydroxy-(5Z,8E,10E)-heptadecatrienoate + malonaldehyde

Left to rightBalancedRhea 48644

lipoxin A4 + reduced [NADPH--hemoprotein reductase] + O2 = 20-hydroxy-lipoxin A4 + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 48648

lipoxin B4 + reduced [NADPH--hemoprotein reductase] + O2 = 20-hydroxy-lipoxin B4 + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 48652

5-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 5,20-dihydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 48656

8-hydroxy-(5Z,9E,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 8,20-dihydroxy-(5Z,9E,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 48660

12-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 12,20-dihydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 48664

20-hydroxy-leukotriene B4 + reduced [NADPH--hemoprotein reductase] + O2 = 20-oxo-leukotriene B4 + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Left to rightBalance undeterminableRhea 48668

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