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CompoundsSubstances with curated findings
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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

8,801–8,850 of 18,558 reactions from Rhea

progesterone + reduced [NADPH--hemoprotein reductase] + O2 = 6beta-hydroxyprogesterone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Left to rightBalance undeterminableRhea 47252
androst-4-ene-3,17-dione + reduced [NADPH--hemoprotein reductase] + O2 = 6beta-hydroxyandrost-4-ene-3,17-dione + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Left to rightBalance undeterminableRhea 47256
progesterone + reduced [NADPH--hemoprotein reductase] + O2 = 16alpha-hydroxyprogesterone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Left to rightBalance undeterminableRhea 47260
2,6,10,14-tetramethylpentadecanoate + ATP + CoA = pristanoyl-CoA + AMP + diphosphate
Left to rightBalancedRhea 47264
bacterioruberin = monoanhydrobacterioruberin + H2O
Direction not assertedBalancedRhea 47268
monoanhydrobacterioruberin = bisanhydrobacterioruberin + H2O
Direction not assertedBalancedRhea

47272

17beta-estradiol + reduced [NADPH--hemoprotein reductase] + O2 = 15alpha-hydroxy-17beta-estradiol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 47276

17beta-estradiol + reduced [NADPH--hemoprotein reductase] + O2 = 4-hydroxy-17beta-estradiol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 47280

17beta-estradiol + reduced [NADPH--hemoprotein reductase] + O2 = 6alpha-hydroxy-17beta-estradiol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 47284

17beta-estradiol + reduced [NADPH--hemoprotein reductase] + O2 = 7alpha-hydroxy-17beta-estradiol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 47288

estrone + reduced [NADPH--hemoprotein reductase] + O2 = 4-hydroxyestrone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 47292

dodecanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-dodecenoyl-CoA + reduced [electron-transfer flavoprotein]

Left to rightBalance undeterminableRhea 47296

oxidized [electron-transfer flavoprotein] + (9Z)-octadecenoyl-CoA + H(+) = (2E,9Z)-octadecadienoyl-CoA + reduced [electron-transfer flavoprotein]

Left to rightBalance undeterminableRhea 47300

(9Z)-hexadecenoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,9Z)-hexadecadienoyl-CoA + reduced [electron-transfer flavoprotein]

Left to rightBalance undeterminableRhea 47304

estrone + reduced [NADPH--hemoprotein reductase] + O2 = 6alpha-hydroxyestrone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 47308

estrone + reduced [NADPH--hemoprotein reductase] + O2 = 15alpha-hydroxyestrone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 47312

tetradecanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-tetradecenoyl-CoA + reduced [electron-transfer flavoprotein]

Left to rightBalance undeterminableRhea 47316

(S)-3-amino-3-phenylpropanoate + 2-oxoglutarate = 3-oxo-3-phenylpropanoate + L-glutamate

Direction not assertedBalancedRhea 47320

(S)-3-amino-3-phenylpropanoate + pyruvate = 3-oxo-3-phenylpropanoate + L-alanine

Direction not assertedBalancedRhea 47324

1,2-di-(9Z)-octadecenoyl-sn-glycero-3-phospho-L-serine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + (9Z)-octadecenoate + H(+)

Direction not assertedBalancedRhea 47328

17beta-estradiol + reduced [NADPH--hemoprotein reductase] + O2 = 16alpha,17beta-estriol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 47332

17beta-estradiol + reduced [NADPH--hemoprotein reductase] + O2 = 16beta,17beta-estriol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 47336

estrone + reduced [NADPH--hemoprotein reductase] + O2 = 6beta-hydroxyestrone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 47340

7-oxocholesterol + 2 reduced [adrenodoxin] + O2 + 2 H(+) = (25R)-3beta,26-dihydroxycholest-5-en-7-one + 2 oxidized [adrenodoxin] + H2O

Left to rightBalance undeterminableRhea 47344

a butanoate ester + H2O = an aliphatic alcohol + butanoate + H(+)

Left to rightBalance undeterminableRhea 47348

a hexanoate ester + H2O = an aliphatic alcohol + hexanoate + H(+)

Direction not assertedBalance undeterminableRhea 47352

an octanoate ester + H2O = an aliphatic alcohol + octanoate + H(+)

Direction not assertedBalance undeterminableRhea 47356

decanoate ester + H2O = decanoate + an aliphatic alcohol + H(+)

Direction not assertedBalance undeterminableRhea 47360

a dodecanoate ester + H2O = an aliphatic alcohol + dodecanoate + H(+)

Direction not assertedBalance undeterminableRhea 47364

a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + GDP-alpha-D-mannose = a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-mannopyranosyl-(1<->6)-D-myo-inositol] + GDP + H(+)

Direction not assertedBalance undeterminableRhea 47368

a quinone + D-glucose = D-glucono-1,5-lactone + a quinol

Direction not assertedBalance undeterminableRhea 47372

(25R)-3beta,26-dihydroxycholest-5-en-7-one + 2 reduced [adrenodoxin] + O2 + 2 H(+) = (25R)-3beta-hydroxycholest-5-en-7-one-26-al + 2 oxidized [adrenodoxin] + 2 H2O

Left to rightBalance undeterminableRhea 47376

(25R)-3beta-hydroxycholest-5-en-7-one-26-al + 2 reduced [adrenodoxin] + O2 + H(+) = (25R)-3beta-hydroxycholest-5-en-7-one-26-oate + 2 oxidized [adrenodoxin] + H2O

Left to rightBalance undeterminableRhea 47380

4-acetoxyphenol + H2O = hydroquinone + acetate + H(+)

Direction not assertedBalancedRhea 47384

a tetradecanoate ester + H2O = an aliphatic alcohol + tetradecanoate + H(+)

Direction not assertedBalance undeterminableRhea 47388

hexadecanoate ester + H2O = an aliphatic alcohol + hexadecanoate + H(+)

Left to rightBalance undeterminableRhea 47392

octadecanoate ester + H2O = an aliphatic alcohol + octadecanoate + H(+)

Direction not assertedBalance undeterminableRhea 47396

3-oxo-(9Z-octadecenoyl)-CoA + CoA = (7Z)-hexadecenoyl-CoA + acetyl-CoA

Left to rightBalancedRhea 47400

(24R,25R)-3alpha,7alpha,24-trihydroxy-5beta-cholestan-26-oyl-CoA + NAD(+) = 3alpha,7alpha-dihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 47404

(24E)-3alpha,7alpha-dihydroxy-5beta-cholest-24-en-26-oyl-CoA + H2O = (24R,25R)-3alpha,7alpha,24-trihydroxy-5beta-cholestan-26-oyl-CoA

Direction not assertedBalancedRhea 47408

a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-mannopyranosyl-(1<->6)-D-myo-inositol] + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-6-acyl-mannopyranosyl-(1<->6)-D-myo-inositol] + CoA

Direction not assertedBalance undeterminableRhea 47412

an NDP-alpha-D-glucose + D-glucose = alpha,alpha-trehalose + a ribonucleoside 5'-diphosphate + H(+)

Direction not assertedBalance undeterminableRhea 47416

glutaryl-CoA + A = (2E)-glutaconyl-CoA + AH2

Direction not assertedBalancedRhea 47420

(2E,9Z)-octadecadienoyl-CoA + H2O = (3S)-hydroxy-(9Z-octadecenoyl)-CoA

Left to rightBalancedRhea 47424

(3S)-hydroxy-(9Z-octadecenoyl)-CoA + NAD(+) = 3-oxo-(9Z-octadecenoyl)-CoA + NADH + H(+)

Left to rightBalancedRhea 47428

(7Z)-hexadecenoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,7Z)-hexadecadienoyl-CoA + reduced [electron-transfer flavoprotein]

Left to rightBalance undeterminableRhea 47432

(2E,7Z)-hexadecadienoyl-CoA + H2O = (3S)-hydroxy-(7Z-hexadecenoyl)-CoA

Left to rightBalancedRhea 47436

(3S)-hydroxy-(7Z-hexadecenoyl)-CoA + NAD(+) = 3-oxo-(7Z-hexadecenoyl)-CoA + NADH + H(+)

Left to rightBalancedRhea 47440

3-oxo-(7Z-hexadecenoyl)-CoA + CoA = (5Z)-tetradecenoyl-CoA + acetyl-CoA

Left to rightBalancedRhea 47444

(5Z)-tetradecenoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,5Z)-tetradecadienoyl-CoA + reduced [electron-transfer flavoprotein]

Left to rightBalance undeterminableRhea 47448

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