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6,501–6,550 of 12,877 reactions from Human-GEM
3,4-dihydroxyphenylethyleneglycol[c] + SAM[c] = 3-methoxy-4-hydroxyphenylethyleneglycol[c] + H+[c] + SAH[c]
Left to rightBalancedEC 2.1.1.6Phenylalanine, tyrosine and tryptophan biosynthesisHuman-GEM MAR06757
dopamine[c] + H2O[c] + O2[c] = 3,4-dihydroxyphenylacetaldehyde[c] + H+[c] + H2O2[c] + NH3[c]
Left to rightBalancedEC 1.4.3.4, 1.4.3.21, 1.4.3.22Phenylalanine, tyrosine and tryptophan biosynthesisHuman-GEM MAR06758
3,4-dihydroxyphenylacetaldehyde[c] + dopamine[c] = H2O[c] + norlaudanosoline[c]
ReversibleBalancedEC 3.5.99.14Phenylalanine, tyrosine and tryptophan biosynthesisHuman-GEM MAR06759
3,4-dihydroxyphenylacetaldehyde[c] + H2O[c] + NAD+[c] = 3,4-dihydroxyphenylacetate[c] + 2 H+[c] + NADH[c]
Left to right
3,4-dihydroxyphenylacetaldehyde[c] + H2O[c] + NADP+[c] = 3,4-dihydroxyphenylacetate[c] + 2 H+[c] + NADPH[c]
Left to rightBalancedEC 1.2.1.5Phenylalanine, tyrosine and tryptophan biosynthesisHuman-GEM MAR06761
3,4-dihydroxyphenylacetate[c] + SAM[c] = H+[c] + homovanillate[c] + SAH[c]
Left to rightBalancedEC 2.1.1.6Phenylalanine, tyrosine and tryptophan biosynthesisHuman-GEM MAR06762
dopamine[c] + SAM[c] = 3-methoxytyramine[c] + H+[c] + SAH[c]
Left to rightBalancedEC 2.1.1.6Phenylalanine, tyrosine and tryptophan biosynthesisHuman-GEM MAR06763
3-methoxytyramine[c] + H2O[c] + O2[c] = 3-methoxy-4-hydroxyphenylacetaldehyde[c] + H+[c] + H2O2[c] + NH3[c]
Left to rightBalancedEC 1.4.3.4Phenylalanine, tyrosine and tryptophan biosynthesisHuman-GEM MAR06764
3-methoxytyramine[c] + acetaldehyde[c] = H2O[c] + N-methylsalsolinol[c]
ReversibleBalancedPhenylalanine, tyrosine and tryptophan biosynthesisHuman-GEM MAR06765
3-methoxy-4-hydroxyphenylacetaldehyde[c] + H2O[c] + NAD+[c] = 2 H+[c] + homovanillate[c] + NADH[c]
Left to rightBalancedEC 1.2.1.5Phenylalanine, tyrosine and tryptophan biosynthesisHuman-GEM MAR06766
3-methoxy-4-hydroxyphenylacetaldehyde[c] + H2O[c] + NADP+[c] = 2 H+[c] + homovanillate[c] + NADPH[c]
Left to rightBalancedEC 1.2.1.5Phenylalanine, tyrosine and tryptophan biosynthesisHuman-GEM MAR06767
AKG[c] + tyrosine[c] = 4-hydroxyphenylpyruvate[c] + glutamate[c]
Left to rightBalancedEC 2.6.1.1, 2.6.1.5, 2.6.1.57Phenylalanine, tyrosine and tryptophan biosynthesisHuman-GEM MAR06768
22-hydroxydocosanoic acid[r] = 22-hydroxydocosanoic acid[c]
ReversibleBalancedTransportFatty acid oxidationHuman-GEM MAR06769
H2O[c] + O2[c] + tyrosine[c] = 4-hydroxyphenylpyruvate[c] + H+[c] + H2O2[c] + NH3[c]
Left to rightBalancedEC 1.4.3.2Phenylalanine, tyrosine and tryptophan biosynthesisHuman-GEM MAR06770
4-hydroxyphenylpyruvate[c] = 2-hydroxy-3-(4-hydroxyphenyl)propenoate[c]
Left to rightBalancedEC 5.3.2.1Phenylalanine, tyrosine and tryptophan biosynthesisHuman-GEM MAR06771
4-hydroxyphenylpyruvate[c] + O2[c] = CO2[c] + homogentisate[c]
Left to rightBalancedEC 1.13.11.27Phenylalanine, tyrosine and tryptophan biosynthesisHuman-GEM MAR06772
16-hydroxyhexadecanoic acid[r] = 16-hydroxyhexadecanoic acid[c]
ReversibleBalancedTransportFatty acid oxidationHuman-GEM MAR06773
homogentisate[c] + O2[c] = 4-maleylacetoacetate[c] + H+[c]
Left to rightBalancedEC 1.13.11.5Phenylalanine, tyrosine and tryptophan biosynthesisHuman-GEM MAR06774
ATP[c] + H2O[c] + pristanoyl-CoA[c] = ADP[c] + H+[c] + Pi[c] + pristanoyl-CoA[x]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR06775
4-maleylacetoacetate[c] = fumarylacetoacetate[c]
Left to rightBalancedEC 5.2.1.2Phenylalanine, tyrosine and tryptophan biosynthesisHuman-GEM MAR06776
H2O[x] + suberyl-CoA[x] = CoA[x] + H+[x] + suberic acid[x]
Left to rightBalancedEC 3.1.2.-Fatty acid oxidationHuman-GEM MAR06777
fumarylacetoacetate[c] + H2O[c] = acetoacetate[c] + fumarate[c] + H+[c]
Left to rightBalancedEC 3.7.1.2Phenylalanine, tyrosine and tryptophan biosynthesisHuman-GEM MAR06778
ATP[c] + 2 H2O[c] + 3(S)-phytanoyl-CoA[c] = ADP[c] + CoA[c] + H+[c] + Pi[c] + Dibenzo[A,L]Pyrene-11,12-Diol[x]
Left to rightUnbalancedTransport reactionsHuman-GEM MAR06779
AKG[m] + tyrosine[m] = 4-hydroxyphenylpyruvate[m] + glutamate[m]
Left to rightBalancedEC 2.6.1.5, 2.6.1.57, 2.6.1.1Alanine, aspartate and glutamate metabolismHuman-GEM MAR06780
4-hydroxyphenylpyruvate[c] + H+[c] = 4-hydroxyphenylpyruvate[m] + H+[m]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR06781
4-hydroxyphenylpyruvate[c] + H+[c] + NADH[c] = 4-hydroxyphenyllactate[c] + NAD+[c]
Left to rightBalancedEC 1.1.1.110, 1.1.1.237Phenylalanine, tyrosine and tryptophan biosynthesisHuman-GEM MAR06782
4-hydroxyphenyllactate[c] = 4-coumarate[c] + H2O[c]
Left to rightBalancedPhenylalanine, tyrosine and tryptophan biosynthesisHuman-GEM MAR06783
4-coumarate[c] + ATP[c] + CoA[c] = 4-coumaroyl-CoA[c] + AMP[c] + PPi[c]
Left to rightBalancedEC 6.2.1.12Phenylalanine, tyrosine and tryptophan biosynthesisHuman-GEM MAR06784
4-coumaroyl-CoA[c] + CoA[c] + H2O[c] + NAD+[c] = 4-hydroxybenzoyl-CoA[c] + acetyl-CoA[c] + H+[c] + NADH[c]
Left to rightBalancedPhenylalanine, tyrosine and tryptophan biosynthesisHuman-GEM MAR06785
4-hydroxybenzoyl-CoA[c] + H2O[c] = 4-hydroxybenzoate[c] + CoA[c] + H+[c]
Left to rightBalancedEC 3.1.2.23Phenylalanine, tyrosine and tryptophan biosynthesisHuman-GEM MAR06786
H+[c] + tyrosine[c] = CO2[c] + tyramine[c]
Left to rightBalancedEC 4.1.1.28Phenylalanine, tyrosine and tryptophan biosynthesisHuman-GEM MAR06787
SAM[c] + tyramine[c] = H+[c] + N-methyltyramine[c] + SAH[c]
Left to rightBalancedEC 2.1.1.49, 2.1.1.6Phenylalanine, tyrosine and tryptophan biosynthesisHuman-GEM MAR06788
H2O[c] + O2[c] + tyramine[c] = 4-hydroxyphenylacetaldehyde[c] + H+[c] + H2O2[c] + NH3[c]
Left to rightBalancedEC 1.4.3.4, 1.4.3.21Phenylalanine, tyrosine and tryptophan biosynthesisHuman-GEM MAR06789
4-hydroxyphenylacetaldehyde[c] + H2O[c] + NAD+[c] = 4-hydroxyphenylacetate[c] + 2 H+[c] + NADH[c]
Left to rightBalancedEC 1.2.1.5Phenylalanine, tyrosine and tryptophan biosynthesisHuman-GEM MAR06790
4-hydroxyphenylacetaldehyde[c] + H2O[c] + NADP+[c] = 4-hydroxyphenylacetate[c] + 2 H+[c] + NADPH[c]
Left to rightBalancedEC 1.2.1.5Phenylalanine, tyrosine and tryptophan biosynthesisHuman-GEM MAR06791
4-hydroxy-3-nitrophenylacetate[c] + 2 H+[c] = 4-hydroxyphenylacetate[c] + nitrite[c]
ReversibleUnbalancedPhenylalanine, tyrosine and tryptophan biosynthesisHuman-GEM MAR06792
iodine[c] + tyrosine[c] = 3-iodo-L-tyrosine[c] + H+[c] + hydroiodic acid[c]
Left to rightBalancedEC 1.11.1.8Steroid metabolismHuman-GEM MAR06793
3-iodo-L-tyrosine[c] + iodine[c] = 3,5-diiodo-L-tyrosine[c] + H+[c] + hydroiodic acid[c]
Left to rightBalancedEC 1.11.1.8Steroid metabolismHuman-GEM MAR06794
2 3,5-diiodo-L-tyrosine[c] + H2O2[c] = dehydroalanine[c] + 2 H2O[c] + thyroxine[c]
Left to rightBalancedEC 1.11.1.8Steroid metabolismHuman-GEM MAR06795
3,5-diiodo-L-tyrosine[c] + 3-iodo-L-tyrosine[c] + H2O2[c] = dehydroalanine[c] + 2 H2O[c] + triiodothyronine[c]
Left to rightBalancedEC 1.11.1.8Steroid metabolismHuman-GEM MAR06796
triiodothyronine[c] = triiodothyronine[r]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR06797
3,5,3-triiodo-L-thyronine-beta-D-glucuronoside[c] + H+[c] + UDP[c] = triiodothyronine[c] + UDP-glucuronate[c]
ReversibleBalancedEC 2.4.1.17Phenylalanine, tyrosine and tryptophan biosynthesisHuman-GEM MAR06798
triiodothyronine[r] + UDP-glucuronate[r] = 3,5,3-triiodo-L-thyronine-beta-D-glucuronoside[r] + H+[r] + UDP[r]
Left to rightBalancedEC 2.4.1.17Phenylalanine, tyrosine and tryptophan biosynthesisHuman-GEM MAR06799
3,5,3,5-tetraiodo-L-thyronine-beta-D-glucuronoside[c] + H+[c] + UDP[c] = thyroxine[c] + UDP-glucuronate[c]
ReversibleBalancedEC 2.4.1.17Phenylalanine, tyrosine and tryptophan biosynthesisHuman-GEM MAR06800
thyroxine[r] + UDP-glucuronate[r] = 3,5,3,5-tetraiodo-L-thyronine-beta-D-glucuronoside[r] + H+[r] + UDP[r]
Left to rightBalancedEC 2.4.1.17Phenylalanine, tyrosine and tryptophan biosynthesisHuman-GEM MAR06801
N-methyltyramine[c] + SAM[c] = H+[c] + hordenine[c] + SAH[c]
Left to rightBalancedEC 2.1.1.-Phenylalanine, tyrosine and tryptophan biosynthesisHuman-GEM MAR06802
hordenine[c] + O2[c] = H2O[c] + N,N-dimethyldopaminequinone[c]
Left to rightBalancedEC 1.14.18.1Phenylalanine, tyrosine and tryptophan biosynthesisHuman-GEM MAR06803
ATP[c] + CoA[c] + sebacic acid[c] = AMP[c] + PPi[c] + sebacoyl-CoA[c]
Left to rightBalancedFatty acid oxidationHuman-GEM MAR06804
sebacic acid[x] = sebacic acid[c]
ReversibleBalancedTransportFatty acid oxidationHuman-GEM MAR06805
2 H+[c] + N,N-dimethylindoliumolate[c] = N,N-dimethyldopaminequinone[c]
ReversibleUnbalancedPhenylalanine, tyrosine and tryptophan biosynthesisHuman-GEM MAR06806