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6,201–6,250 of 12,877 reactions from Human-GEM
13-carboxy-gamma-tocotrienol[m] + ATP[m] + CoA[m] + 2 H2O[m] + NAD+[m] = 11-carboxy-gamma-tocotrienol[m] + AMP[m] + 2 H+[m] + NADH[m] + PPi[m] + propanoyl-CoA[m]
Left to rightBalancedVitamin E metabolismHuman-GEM MAR06447
11-carboxy-gamma-tocotrienol[m] + ATP[m] + CoA[m] + 2 H2O[m] + NAD+[m] + O2[m] = 9-carboxy-gamma-tocotrienol[m] + acetyl-CoA[m] + AMP[m] + 2 H+[m] + H2O2[m] + NADH[m] + PPi[m]
Left to rightBalancedEC 1.1.1.35, 1.3.1.34, 1.3.3.6, 2.3.1.16, 3.1.2.2, 3.1.2.27, 4.2.1.17, 5.1.99.4, 5.3.3.8, 6.2.1.-Vitamin E metabolismHuman-GEM MAR06448
CoA[m] + FAD[m] + H2O[m] + NAD+[m] + trans7,10-hexadecadienoyl-CoA[m] = acetyl-CoA[m] + FADH2[m] + H+[m] + NADH[m] + trans5,8tetradecadienoyl-CoA[m]
Left to rightBalancedFatty acid oxidationHuman-GEM MAR06449
9-carboxy-gamma-tocotrienol[m] + ATP[m] + CoA[m] + 2 H2O[m] + NAD+[m] = 7-carboxy-gamma-tocotrienol[m] + AMP[m] + 2 H+[m] + NADH[m] + PPi[m] + propanoyl-CoA[m]
7-carboxy-gamma-tocotrienol[m] + ATP[m] + CoA[m] + 2 H2O[m] + O2[m] = 5-carboxy-gamma-chromanol[m] + acetyl-CoA[m] + AMP[m] + H+[m] + H2O2[m] + PPi[m]
Left to rightBalancedEC 1.1.1.35, 1.3.1.34, 1.3.3.6, 2.3.1.16, 3.1.2.2, 3.1.2.27, 4.2.1.17, 5.1.99.4, 5.3.3.8, 6.2.1.-Vitamin E metabolismHuman-GEM MAR06451
(6Z,9Z)-octadecadienoyl-CoA[m] + CoA[m] + FAD[m] + H2O[m] + NAD+[m] = acetyl-CoA[m] + FADH2[m] + H+[m] + NADH[m] + trans7,10-hexadecadienoyl-CoA[m]
Left to rightBalancedFatty acid oxidationHuman-GEM MAR06452
5-carboxy-gamma-chromanol[m] + ATP[m] + CoA[m] + 2 H2O[m] + NAD+[m] + O2[m] = AMP[m] + gamma-carboxyethyl-hydroxychroman[m] + 2 H+[m] + H2O2[m] + NADH[m] + PPi[m] + propanoyl-CoA[m]
Left to rightBalancedEC 1.1.1.35, 1.3.3.6, 2.3.1.176, 2.3.1.16, 3.1.2.2, 4.2.1.17, 5.1.99.4, 6.2.1.-Vitamin E metabolismHuman-GEM MAR06453
gamma-carboxyethyl-hydroxychroman[m] = gamma-carboxyethyl-hydroxychroman[c]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR06454
5-carboxy-gamma-chromanol[m] + H+[m] = 5-carboxy-gamma-chromanol[c] + H+[c]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR06455
gamma-tocopheroxyl-radical[c] + H+[c] = gamma-tocopherol[c]
ReversibleUnbalancedVitamin E metabolismHuman-GEM MAR06456
8alpha-hydroxy-gamma-tocopherone[c] = gamma-tocopheroxyl-radical[c] + hydroxide[c]
ReversibleUnbalancedVitamin E metabolismHuman-GEM MAR06457
8alpha-hydroxy-gamma-tocopherone[c] = gamma-tocopheryl-quinone[c]
ReversibleBalancedVitamin E metabolismHuman-GEM MAR06458
5-nitro-gamma-tocopherol[c] = gamma-tocopheroxyl-radical[c] + nitrite[c]
ReversibleUnbalancedVitamin E metabolismHuman-GEM MAR06459
5-nitro-gamma-tocopherol[c] + H2O[c] = gamma-tocopherol[c] + H+[c] + peroxynitrite[c]
ReversibleBalancedVitamin E metabolismHuman-GEM MAR06460
nitrosoperoxycarbonate[c] = CO2[c] + peroxynitrite[c]
Left to rightBalancedVitamin E metabolismHuman-GEM MAR06461
gamma-tocopherol[c] = gamma-tocopherol[e]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR06462
gamma-tocopherol[c] = gamma-tocopherol[r]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR06463
gamma-tocopherol[c] + H+[c] + NADPH[c] + O2[c] = 13-hydroxy-gamma-tocopherol[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.94Vitamin E metabolismHuman-GEM MAR06464
gamma-tocopherol[r] + H+[r] + NADPH[r] + O2[r] = 13-hydroxy-gamma-tocopherol[r] + H2O[r] + NADP+[r]
Left to rightBalancedEC 1.14.14.94Vitamin E metabolismHuman-GEM MAR06465
13-hydroxy-gamma-tocopherol[c] + H+[c] + 2 NADPH[c] + 2 O2[c] = 13-carboxy-gamma-tocopherol[c] + 3 H2O[c] + 2 NADP+[c]
Left to rightBalancedEC 1.14.14.94Vitamin E metabolismHuman-GEM MAR06466
13-hydroxy-gamma-tocopherol[r] + H+[r] + 2 NADPH[r] + 2 O2[r] = 13-carboxy-gamma-tocopherol[r] + 3 H2O[r] + 2 NADP+[r]
Left to rightBalancedEC 1.14.14.94Vitamin E metabolismHuman-GEM MAR06467
13-carboxy-gamma-tocopherol[c] = 13-carboxy-gamma-tocopherol[r]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR06468
13-carboxy-gamma-tocopherol[c] = 13-carboxy-gamma-tocopherol[m]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR06469
13-carboxy-gamma-tocopherol[m] + ATP[m] + CoA[m] + 2 H2O[m] + NAD+[m] + O2[m] = 11-carboxy-gamma-chromanol[m] + AMP[m] + 2 H+[m] + H2O2[m] + NADH[m] + PPi[m] + propanoyl-CoA[m]
Left to rightBalancedVitamin E metabolismHuman-GEM MAR06470
11-carboxy-gamma-chromanol[m] + ATP[m] + CoA[m] + 2 H2O[m] + NAD+[m] + O2[m] = 9-carboxy-gamma-chromanol[m] + acetyl-CoA[m] + AMP[m] + 2 H+[m] + H2O2[m] + NADH[m] + PPi[m]
Left to rightBalancedEC 1.1.1.35, 1.3.3.6, 2.3.1.176, 2.3.1.16, 3.1.2.2, 4.2.1.17, 5.1.99.4, 6.2.1.-Vitamin E metabolismHuman-GEM MAR06471
9-carboxy-gamma-chromanol[m] + ATP[m] + CoA[m] + 2 H2O[m] + NAD+[m] + O2[m] = 7-carboxy-gamma-chromanol[m] + AMP[m] + 2 H+[m] + H2O2[m] + NADH[m] + PPi[m] + propanoyl-CoA[m]
Left to rightBalancedEC 1.1.1.35, 1.3.3.6, 2.3.1.176, 2.3.1.16, 3.1.2.2, 4.2.1.17, 5.1.99.4, 6.2.1.-Vitamin E metabolismHuman-GEM MAR06472
7-carboxy-gamma-chromanol[m] + ATP[m] + CoA[m] + 2 H2O[m] + NAD+[m] + O2[m] = 5-carboxy-gamma-chromanol[m] + acetyl-CoA[m] + AMP[m] + 2 H+[m] + H2O2[m] + NADH[m] + PPi[m]
Left to rightBalancedEC 1.1.1.35, 1.3.3.6, 2.3.1.176, 2.3.1.16, 3.1.2.2, 4.2.1.17, 5.1.99.4, 6.2.1.-Vitamin E metabolismHuman-GEM MAR06473
alpha-tocopherol[c] = alpha-tocopherol[e]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR06474
alpha-tocopherol[c] = alpha-tocopherol[r]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR06475
alpha-tocopherol[c] + H+[c] + NADPH[c] + O2[c] = 13-hydroxy-alpha-tocopherol[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.94Vitamin E metabolismHuman-GEM MAR06476
alpha-tocopherol[r] + H+[r] + NADPH[r] + O2[r] = 13-hydroxy-alpha-tocopherol[r] + H2O[r] + NADP+[r]
Left to rightBalancedEC 1.14.14.94Vitamin E metabolismHuman-GEM MAR06477
13-hydroxy-alpha-tocopherol[c] + H+[c] + 2 NADPH[c] + 2 O2[c] = 13-carboxy-alpha-tocopherol[c] + 3 H2O[c] + 2 NADP+[c]
Left to rightBalancedEC 1.14.14.94Vitamin E metabolismHuman-GEM MAR06478
13-hydroxy-alpha-tocopherol[r] + H+[r] + 2 NADPH[r] + 2 O2[r] = 13-carboxy-alpha-tocopherol[r] + 3 H2O[r] + 2 NADP+[r]
Left to rightBalancedEC 1.14.14.94Vitamin E metabolismHuman-GEM MAR06479
13-carboxy-alpha-tocopherol[r] = 13-carboxy-alpha-tocopherol[c]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR06480
13-carboxy-alpha-tocopherol[c] = 13-carboxy-alpha-tocopherol[m]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR06481
13-carboxy-alpha-tocopherol[m] + ATP[m] + CoA[m] + 2 H2O[m] + NAD+[m] + O2[m] = 11-carboxy-alpha-chromanol[m] + AMP[m] + 2 H+[m] + H2O2[m] + NADH[m] + PPi[m] + propanoyl-CoA[m]
Left to rightBalancedVitamin E metabolismHuman-GEM MAR06482
CoA[x] + H2O[x] + NAD+[x] + 2,6-dodecadienoyl-CoA[x] = 4-cis-decenoyl-CoA[x] + acetyl-CoA[x] + H+[x] + NADH[x]
Left to rightBalancedFatty acid oxidationHuman-GEM MAR06483
11-carboxy-alpha-chromanol[m] + ATP[m] + CoA[m] + 2 H2O[m] + NAD+[m] + O2[m] = 9-carboxy-alpha-chromanol[m] + acetyl-CoA[m] + AMP[m] + 2 H+[m] + H2O2[m] + NADH[m] + PPi[m]
Left to rightBalancedEC 1.1.1.35, 1.3.3.6, 2.3.1.176, 2.3.1.16, 3.1.2.2, 4.2.1.17, 5.1.99.4, 6.2.1.-Vitamin E metabolismHuman-GEM MAR06484
glutaryl-CoA[m] = glutaryl-CoA[c]
ReversibleBalancedTransportFatty acid oxidationHuman-GEM MAR06485
9-carboxy-alpha-chromanol[m] + ATP[m] + CoA[m] + 2 H2O[m] + NAD+[m] + O2[m] = 7-carboxy-alpha-chromanol[m] + AMP[m] + 2 H+[m] + H2O2[m] + NADH[m] + PPi[m] + propanoyl-CoA[m]
Left to rightBalancedEC 1.1.1.35, 1.3.3.6, 2.3.1.176, 2.3.1.16, 3.1.2.2, 4.2.1.17, 5.1.99.4, 6.2.1.-Vitamin E metabolismHuman-GEM MAR06486
(S)-hydroxydecanoyl-CoA[m] = (S)-hydroxydecanoyl-CoA[c]
ReversibleBalancedTransportFatty acid oxidationHuman-GEM MAR06487
7-carboxy-alpha-chromanol[m] + ATP[m] + CoA[m] + 2 H2O[m] + NAD+[m] + O2[m] = 5-carboxy-alpha-chromanol[m] + acetyl-CoA[m] + AMP[m] + 2 H+[m] + H2O2[m] + NADH[m] + PPi[m]
Left to rightBalancedVitamin E metabolismHuman-GEM MAR06488
(S)-3-hydroxydodecanoyl-CoA[m] = (S)-3-hydroxydodecanoyl-CoA[c]
ReversibleBalancedTransportFatty acid oxidationHuman-GEM MAR06489
gamma-carboxyethyl-hydroxychroman[c] + UDP-glucuronate[c] = gamma-CEHC-glucuronide[c] + UDP[c]
Left to rightBalancedEC 2.4.1.17Vitamin E metabolismHuman-GEM MAR06490
3-hydroxyhexadecanoyl-CoA[m] = 3-hydroxyhexadecanoyl-CoA[c]
ReversibleBalancedTransportFatty acid oxidationHuman-GEM MAR06491
gamma-CEHC-glucuronide[c] + H2O[c] = gamma-carboxyethyl-hydroxychroman[c] + glucuronate[c] + H+[c]
ReversibleBalancedEC 3.2.1.31Vitamin E metabolismHuman-GEM MAR06492
3-hydroxyhexadecenoyl-CoA[m] = 3-hydroxyhexadecenoyl-CoA[c]
ReversibleBalancedTransportFatty acid oxidationHuman-GEM MAR06493
3-carboxy-alpha-chromanol[c] + UDP-glucuronate[c] = alpha-CEHC-glucuronide[c] + UDP[c]
Left to rightBalancedEC 2.4.1.17Vitamin E metabolismHuman-GEM MAR06495
alpha-CEHC-glucuronide[c] + H2O[c] = 3-carboxy-alpha-chromanol[c] + glucuronate[c] + H+[c]
Left to rightBalancedEC 3.2.1.31Vitamin E metabolismHuman-GEM MAR06496
Hexadecanediocacid[c] = Hexadecanediocacid[r]
ReversibleBalancedTransportFatty acid oxidationHuman-GEM MAR06498