Reactions
AKR1C1
48 reactions
- MAM00339c + NADP(3-) ⇌ MAM00394c + proton + NADPH(4-)
⇌ Balanced · EC 1.1.1.-
- MAM01177c + proton + NADPH(4-) → MAM01078c + NADP(3-)
→ Balanced · EC 1.1.1.50, 1.1.1.213
- MAM01181c + proton + NADPH(4-) → MAM01095c + NADP(3-)
→ Balanced · EC 1.1.1.213, 1.1.1.50
- MAM00747r + proton + NADPH(4-) ⇌ MAM01087r + NADP(3-)
⇌ Balanced · EC 1.1.1.-
- 3alpha-hydroxy-5alpha-pregnan-20-one + NADP(3-) ⇌ 5alpha-pregnane-3,20-dione + proton + NADPH(4-)
⇌ Balanced · EC 1.1.1.213
- 5alpha-androstan-3,17-dione + proton + NADH(2-) → androsterone + NAD(+)
→ Balanced · EC 1.1.1.209, 1.1.1.213, 1.1.1.50
- 5alpha-androstan-3,17-dione + proton + NADH(2-) → androsterone + NAD(+)
→ Balanced · EC 1.1.1.209, 1.1.1.213, 1.1.1.50
- 5alpha-androstan-3,17-dione + proton + NADPH(4-) → androsterone + NADP(3-)
→ Balanced · EC 1.1.1.209, 1.1.1.213, 1.1.1.50
- 5alpha-androstan-3,17-dione + proton + NADPH(4-) → androsterone + NADP(3-)
→ Balanced · EC 1.1.1.209, 1.1.1.213, 1.1.1.50
- MAM01029c + proton + NADPH(4-) ⇌ MAM01229c + NADP(3-)
⇌ Balanced · EC 1.1.1.-
- 4-methyl-2-oxopentanoate + proton + NADH(2-) ⇌ 2-hydroxy-4-methylvaleric acid + NAD(+)
⇌ Balanced · EC 1.1.1.-
- MAM00243c + NADP(3-) → proton + NADPH(4-) + MAM02557c
→ Balanced · EC 1.3.1.20
- MAM00932c + proton + NADPH(4-) → MAM00929c + NADP(3-)
→ Balanced · EC 1.1.1.146, 1.1.1.184, 1.3.1.20
- proton + NADPH(4-) + progesterone → (20R)-20-hydroxypregn-4-en-3-one + NADP(3-)
→ Balanced · EC 1.1.1.149
- (20R)-20-hydroxypregn-4-en-3-one + NAD(+) → proton + NADH(2-) + progesterone
→ Balanced · EC 1.1.1.149
- testosterone + NADP(3-) ← androst-4-ene-3,17-dione + NADPH(4-) + hydron
← Balanced
- (17R,20S)-17,20-dihydroxypregn-4-en-3-one + NAD(1-) ? 17alpha-hydroxyprogesterone + NADH(2-) + hydron
? Balanced
- (17R,20S)-17,20-dihydroxypregn-4-en-3-one + NADP(3-) ← 17alpha-hydroxyprogesterone + NADPH(4-) + hydron
← Balanced
- CHEBI:18329 + NADP(3-) ← 17beta-hydroxy-5alpha-androstan-3-one + NADPH(4-) + hydron
← Balanced
- CHEBI:156384 + NAD(1-) ? CHEBI:17404 + NADH(2-) + hydron
? Balanced
- CHEBI:156384 + NADP(3-) ? CHEBI:17404 + NADPH(4-) + hydron
? Balanced
- CHEBI:10702 + NADP(3-) ? CHEBI:18135 + NADPH(4-) + hydron
? Balanced
- androsterone + NADP(3-) ← 5alpha-androstan-3,17-dione + NADPH(4-) + hydron
← Balanced
- CHEBI:16229 + NADP(3-) ← 5beta-pregnan-3,20-dione + NADPH(4-) + hydron
← Balanced
- 17beta-estradiol + NAD(1-) ⇌ estrone + NADH(2-) + hydron
⇌ Balanced
- 17beta-estradiol + NADP(3-) ← estrone + NADPH(4-) + hydron
← Balanced
- CHEBI:36835 + NADP(3-) ← CHEBI:47788 + NADPH(4-) + hydron
← Balance undeterminable
- CHEBI:36836 + NADP(3-) ← CHEBI:47788 + NADPH(4-) + hydron
← Balance undeterminable
- 5alpha-androstane-3alpha,17beta-diol + NAD(1-) ← 17beta-hydroxy-5alpha-androstan-3-one + NADH(2-) + hydron
← Balanced
- (20S)-hydroxypregn-4-en-3-one + NAD(1-) ? progesterone + NADH(2-) + hydron
? Balanced
- (20S)-hydroxypregn-4-en-3-one + NADP(3-) ← progesterone + NADPH(4-) + hydron
← Balanced
- 5alpha-androstane-3alpha,17beta-diol + NADP(3-) ← 17beta-hydroxy-5alpha-androstan-3-one + NADPH(4-) + hydron
← Balanced
- 17beta-hydroxy-5alpha-androstan-3-one + NADP(3-) ← 5alpha-androstan-3,17-dione + NADPH(4-) + hydron
← Balanced
- 5alpha-androstane-3alpha,17beta-diol + NAD(1-) ? androsterone + NADH(2-) + hydron
? Balanced
- androsterone + NADPH(4-) + hydron → 5alpha-androstane-3alpha,17beta-diol + NADP(3-)
→ Balanced
- CHEBI:78666 + NADP(3-) ← 5beta-pregnan-3,20-dione + NADPH(4-) + hydron
← Balanced
- CHEBI:136983 + NADP(3-) ← 5alpha-dihydrotestosterone sulfate + NADPH(4-) + hydron
← Balanced
- CHEBI:16229 + NADPH(4-) + hydron → CHEBI:156526 + NADP(3-)
→ Balanced
- CHEBI:1712 + NADP(3-) ← 5beta-pregnan-3,20-dione + NADPH(4-) + hydron
← Balanced
- CHEBI:35343 + NADP(3-) ← CHEBI:19168 + NADPH(4-) + hydron
← Balance undeterminable
- CHEBI:81468 + NADPH(4-) + hydron → CHEBI:34461 + NADP(3-)
→ Balanced
- 5alpha-pregnane-3,20-dione + NADPH(4-) + hydron → 3alpha-hydroxy-5alpha-pregnan-20-one + NADP(3-)
→ Balanced
- 3alpha-hydroxy-5alpha-pregnan-20-one + NADPH(4-) + hydron → CHEBI:81470 + NADP(3-)
→ Balanced
- 5alpha-pregnane-3,20-dione + NADPH(4-) + hydron → 20alpha-hydroxy-5alpha-pregnane-3-one + NADP(3-)
→ Balanced
- CHEBI:1712 + NADPH(4-) + hydron → CHEBI:8387 + NADP(3-)
→ Balanced
- CHEBI:78666 + NADPH(4-) + hydron → CHEBI:8387 + NADP(3-)
→ Balanced
- 20alpha-hydroxy-5alpha-pregnane-3-one + NADPH(4-) + hydron → CHEBI:81470 + NADP(3-)
→ Balanced
- CHEBI:136981 + NADP(3-) ← 5alpha-dihydrotestosterone 17-O-(beta-D-glucuronate) + NADPH(4-) + hydron
← Balanced