Reactions
CYP3A4
185 reactions
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + proton + NADPH(4-) + dioxygen → 7-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + water + NADP(3-)
→ Balanced · EC 1.14.14.1
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + proton + NADPH(4-) + dioxygen → MAM01213c + water + NADP(3-)
→ Balanced · EC 1.14.14.1
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + proton + NADPH(4-) + dioxygen → MAM01239c + water + NADP(3-)
→ Balanced · EC 1.14.14.1
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + proton + NADPH(4-) + dioxygen → 20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + water + NADP(3-)
→ Balanced · EC 1.14.14.1, 1.14.15.3
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + proton + NADPH(4-) + dioxygen → MAM00297c + water + NADP(3-)
→ Balanced · EC 1.14.14.1
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + proton + NADPH(4-) + dioxygen → 13-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + water + NADP(3-)
→ Balanced · EC 1.14.14.1
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + proton + NADPH(4-) + dioxygen → 16(R)-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + water + NADP(3-)
→ Balanced · EC 1.14.14.1
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + proton + NADPH(4-) + dioxygen → 17-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + water + NADP(3-)
→ Balanced · EC 1.14.14.1
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + proton + NADPH(4-) + dioxygen → MAM00426c + water + NADP(3-)
→ Balanced · EC 1.14.14.1
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + proton + NADPH(4-) + dioxygen → MAM00430c + water + NADP(3-)
→ Balanced · EC 1.14.14.1
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + proton + NADPH(4-) + dioxygen → 5,6-epoxy-(8Z,11Z,14Z)-eicosatrienoate + water + NADP(3-)
→ Balanced · EC 1.14.14.1
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + FADH2 + dioxygen → 5,6-epoxy-(8Z,11Z,14Z)-eicosatrienoate + FAD + water
→ Balanced · EC 1.14.14.1
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + FADH2 + dioxygen → 5,6-epoxy-(8Z,11Z,14Z)-eicosatrienoate + FAD + water
→ Balanced · EC 1.14.14.1
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + proton + NADPH(4-) + dioxygen → 8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoate + water + NADP(3-)
→ Balanced · EC 1.14.14.1
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + FADH2 + dioxygen → 8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoate + FAD + water
→ Balanced · EC 1.14.14.1
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + FADH2 + dioxygen → 8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoate + FAD + water
→ Balanced · EC 1.14.14.1
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + proton + NADPH(4-) + dioxygen → MAM00279c + water + NADP(3-)
→ Balanced · EC 1.14.14.1
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + FADH2 + dioxygen → MAM00279c + FAD + water
→ Balanced · EC 1.14.14.1
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + proton + NADPH(4-) + dioxygen → 14,15-epoxy-(5Z,8Z,11Z)-eicosatrienoate + water + NADP(3-)
→ Balanced · EC 1.14.14.1
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + FADH2 + dioxygen → 14,15-epoxy-(5Z,8Z,11Z)-eicosatrienoate + FAD + water
→ Balanced · EC 1.14.14.1
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + FADH2 + dioxygen → 14,15-epoxy-(5Z,8Z,11Z)-eicosatrienoate + FAD + water
→ Balanced · EC 1.14.14.1
- 15(S)-HPETE ⇌ MAM00390c
⇌ Balanced · EC 1.14.14.1
- MAM00276c ⇌ MAM00390c + water
⇌ Balanced · EC 1.14.14.1
- MAM00296c ⇌ 15(S)-HPETE
⇌ Balanced · EC 1.14.14.1
- MAM00280c ⇌ MAM00296c + water
⇌ Balanced · EC 1.14.14.1
- MAM01124c + proton + NADPH(4-) ⇌ MAM01152c + NADP(3-)
⇌ Balanced
- MAM01124m + proton + NADPH(4-) ⇌ MAM01152m + NADP(3-)
⇌ Balanced
- MAM01124r + proton + NADPH(4-) ⇌ MAM01152r + NADP(3-)
⇌ Balanced
- MAM01124x + proton + NADPH(4-) ⇌ MAM01152x + NADP(3-)
⇌ Balanced
- MAM01152c + proton + NADPH(4-) ⇌ MAM01153c + NADP(3-)
⇌ Balanced · EC 1.14.14.1
- MAM01152m + proton + NADPH(4-) ⇌ MAM01153m + NADP(3-)
⇌ Balanced · EC 1.14.14.1
- MAM01152r + proton + NADPH(4-) ⇌ MAM01153r + NADP(3-)
⇌ Balanced · EC 1.14.14.1
- MAM01152x + proton + NADPH(4-) ⇌ MAM01153x + NADP(3-)
⇌ Balanced · EC 1.14.14.1
- MAM01118c + proton + NADPH(4-) ⇌ MAM01151c + NADP(3-)
⇌ Balanced · EC 1.14.14.1
- MAM01118m + proton + NADPH(4-) ⇌ MAM01151m + NADP(3-)
⇌ Balanced · EC 1.14.14.1
- MAM01118r + proton + NADPH(4-) ⇌ MAM01151r + NADP(3-)
⇌ Balanced · EC 1.14.14.1
- MAM01118x + proton + NADPH(4-) ⇌ MAM01151x + NADP(3-)
⇌ Balanced · EC 1.14.14.1
- MAM01078r + proton + NADPH(4-) + dioxygen → MAM01089r + water + NADP(3-)
→ Balanced · EC 1.14.14.55
- MAM01089r + proton + NADPH(4-) + dioxygen → MAM01085r + water + NADP(3-)
→ Balanced · EC 1.14.14.55
- MAM01089r + proton + NADPH(4-) + dioxygen → MAM01086r + water + NADP(3-)
→ Balanced · EC 1.14.14.55
- MAM01089r + proton + NADPH(4-) + dioxygen → MAM01088r + water + NADP(3-)
→ Balanced · EC 1.14.14.55
- 2 proton + lithocholic acid + NADPH(4-) + dioxygen → water + hyodeoxycholate + NADP(3-)
→ Balanced · EC 1.14.14.57
- 17beta-estradiol + proton + NADPH(4-) + dioxygen → 2-hydroxy-17beta-estradiol + water + NADP(3-)
→ Balanced · EC 1.14.14.1
- 17beta-estradiol + proton + NADPH(4-) + dioxygen → 2-hydroxy-17beta-estradiol + water + NADP(3-)
→ Balanced · EC 1.14.14.1
- 17beta-estradiol + proton + NADPH(4-) + dioxygen → 4-hydroxy-17beta-estradiol + water + NADP(3-)
→ Balanced · EC 1.14.14.55
- 17beta-estradiol + proton + NADPH(4-) + dioxygen → 4-hydroxy-17beta-estradiol + water + NADP(3-)
→ Balanced · EC 1.14.14.55
- estrone + proton + NADPH(4-) + dioxygen → MAM01000c + water + NADP(3-)
→ Balanced · EC 1.14.14.55
- estrone + proton + NADPH(4-) + dioxygen → MAM01000l + water + NADP(3-)
→ Balanced · EC 1.14.14.55
- estrone + proton + NADPH(4-) + dioxygen → MAM01000r + water + NADP(3-)
→ Balanced · EC 1.14.14.55
- estrone + proton + NADPH(4-) + dioxygen → 16alpha-hydroxyestrone + water + NADP(3-)
→ Balanced · EC 1.14.14.1