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Proteins/UNIPROT:Q14587
[Isoform 1]: Acts as a transcriptional repressor. Inhibits erythroid differentiation and tumor cell proliferation. Plays a role during ovarian cancer development and progression.
[Isoform 2]: Contributes to cervical carcinogenesis in part through the TNF-induced NF-kappa-B signaling pathway by interacting with the I-kappa-B-kinase (IKK) core complex.
Involved in the regulation of antiviral interferon signaling. During viral infection, recruits SETD4 to TBK1, leading to TBK1 monomethylation, which is critical for the assembly of TBK1 complex and IRF3 signaling..
Function from UniProtKB (Q14587), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
35 statements
35 statements · 3 reference databases · Subject: ZNF268 · Sources: gene ontology, Hetionet, Reactome
2 names
Resolves to: ZNF268