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Proteins/UNIPROT:Q96NT0
Accessory component of the proton-transporting vacuolar (V)-ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation. May be involved in Golgi homeostasis..
Function from UniProtKB (Q96NT0), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
12 statements
12 statements · 2 reference databases · Subject: VMA22 · Sources: Hetionet, Reactome
3 names
Resolves to: VMA22