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Proteins/UNIPROT:P17643
Plays a role in melanin biosynthesis. Catalyzes the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid in the presence of bound Cu(2+) ions, but not in the presence of Zn(2+). May regulate or influence the type of melanin synthesized. Also to a lower extent, capable of hydroxylating tyrosine and producing melanin (By similarity)..
Function from UniProtKB (P17643), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
17 statements
17 statements · 5 reference databases · Subject: TYRP1 · Sources: gene ontology, Hetionet, Reactome, UniProt, WikiPathways
3 reactions
MAM01053cMAM03758c
Catalysed by TYRP1
Reaction pageLeft to rightBalancedEC 1.14.18.-cytosol
Human-GEM MAR01816CC BY 4.0Reference data
MAM01053c+dioxygenMAM01059c+hydrogen peroxide
Reaction pageLeft to rightBalancedEC 1.1.3.-, 1.14.18.1cytosol
Human-GEM MAR06889CC BY 4.0Reference data
2CHEBI:16875
11 names
Resolves to: TYRP1
Reaction pageLeft to rightBalanced
Rhea RHEA:68388CC BY 4.0Reference data