Proteins/UNIPROT:Q9UBN6

TNFRSF10D

ProteinUNIPROT:Q9UBN6

Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway..

Function from UniProtKB (Q9UBN6), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

17 statements

17 statements · 3 reference databases · Subject: TNFRSF10D · Sources: Hetionet, Reactome, WikiPathways

Order

TNFRSF10D interacts with TNFRSF10AProteinHetionet hetionet:interacts:8793-8797Inferred only
TNFRSF10D interacts with TNFRSF10BProteinHetionet hetionet:interacts:8793-8795Inferred only
TNFSF10 interacts with TNFRSF10DProteinHetionet hetionet:interacts:8743-8793Inferred only
UBC interacts with TNFRSF10DProteinHetionet hetionet:interacts:7316-8793Inferred only
TNFRSF10D participates in Apoptosis modulation and signalingPathwayWikiPathways WP1772Inferred only
TNFRSF10D participates in Cell surface interactions at the vascular wallPathwayReactome R-HSA-202733Inferred only
TNFRSF10D participates in Death Receptor SignalingPathwayReactome R-HSA-73887Inferred only
TNFRSF10D participates in Gene expression (Transcription)PathwayReactome R-HSA-74160Inferred only
TNFRSF10D participates in Generic Transcription PathwayPathwayReactome R-HSA-212436Inferred only
TNFRSF10D participates in HemostasisPathwayReactome R-HSA-109582Inferred only
TNFRSF10D participates in p53 transcriptional gene networkPathwayWikiPathways WP4963Inferred only
TNFRSF10D participates in RNA Polymerase II TranscriptionPathwayReactome R-HSA-73857Inferred only

Show the remaining 5

TNFRSF10D participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
TNFRSF10D participates in TP53 Regulates Transcription of Cell Death GenesPathwayReactome R-HSA-5633008Inferred only
TNFRSF10D participates in TP53 Regulates Transcription of Death Receptors and LigandsPathwayReactome R-HSA-6803211Inferred only
TNFRSF10D participates in TRAIL signalingPathwayReactome R-HSA-75158Inferred only
TNFRSF10D participates in Transcriptional Regulation by TP53PathwayReactome R-HSA-3700989Inferred only

Other names

9 names

Resolves to: TNFRSF10D

Also called: CD antigen CD264DCR2Decoy receptor 2TNF-related apoptosis-inducing ligand receptor 4TRAIL receptor 4TRAIL receptor with a truncated death domainTRAIL-R4TRAILR4TRUNDD

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