Proteins/UNIPROT:Q8N0S2

SYCE1

ProteinUNIPROT:Q8N0S2

Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Requires SYCP1 in order to be incorporated into the central element. May have a role in the synaptonemal complex assembly, stabilization and recombination..

Function from UniProtKB (Q8N0S2), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

3 rows

premature ovarian failure 12 has a germline basis in SYCE1DiseaseGenCC HGNC:28852|MONDO:0014844Inferred only
spermatogenic failure 15 has a germline basis in SYCE1DiseaseGenCC HGNC:28852|MONDO:0014847Inferred only
SYCE1-related gametogenic failure has a germline basis in SYCE1DiseaseGenCC HGNC:28852|MONDO:1060214Inferred only

Statements

7 statements

7 statements · 3 reference databases · Subject: SYCE1 · Sources: Hetionet, Reactome, WikiPathways

Order

KBTBD6 covaries with SYCE1ProteinHetionet hetionet:covaries:89890-93426Inferred only
MS4A7 covaries with SYCE1ProteinHetionet hetionet:covaries:58475-93426Inferred only
SYCE1 participates in Cell CyclePathwayReactome R-HSA-1640170Inferred only
SYCE1 participates in MeiosisPathwayReactome R-HSA-1500620Inferred only
SYCE1 participates in Meiotic synapsisPathwayReactome R-HSA-1221632Inferred only
SYCE1 participates in Primary ovarian insufficiencyPathwayWikiPathways WP5461Inferred only
SYCE1 participates in ReproductionPathwayReactome R-HSA-1474165Inferred only

Other names

3 names

Resolves to: SYCE1

Also called: C10orf94Cancer/testis antigen 76CT76

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