SYCE1-related gametogenic failure
MONDO:1060214Mondo
Findings
No curated finding names SYCE1-related gametogenic failure yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
An infertility disorder caused by variation in the SYCE1 gene. Affected males may present with non-obstructive azoospermia due to maturation arrest or meiotic failure, while affected females may present with primary ovarian insufficiency.
Definition from the Mondo Disease Ontology (MONDO:1060214), read 2026-09-29. CC BY 4.0.
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- SYCE1HGNC:28852
- Definitive · ClinGen · Autosomal recessive · 2026
Where it sits
- Narrower terms (2)