Proteins/UNIPROT:Q9NY15

STAB1

ProteinUNIPROT:Q9NY15

Acts as a scavenger receptor for acetylated low density lipoprotein. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. When inhibited in endothelial tube formation assays, there is a marked decrease in cell-cell interactions, suggesting a role in angiogenesis. Involved in the delivery of newly synthesized CHID1/SI-CLP from the biosynthetic compartment to the endosomal/lysosomal system..

Function from UniProtKB (Q9NY15), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

1 row

isolated hyperferritinemia has a germline basis in STAB1DiseaseGenCC HGNC:18628|MONDO:0958237Inferred only

Statements

12 statements

12 statements · 3 reference databases · Subject: STAB1 · Sources: gene ontology, Hetionet, Reactome

Order

STEEP1 covaries with STAB1ProteinHetionet hetionet:covaries:23166-63932Inferred only
STAB1 covaries with ZNF502ProteinHetionet hetionet:covaries:23166-91392Inferred only
STAB1 interacts with CHID1ProteinHetionet hetionet:interacts:23166-66005Inferred only
STAB1 interacts with GGA1ProteinHetionet hetionet:interacts:23166-26088Inferred only
GGA2 interacts with STAB1ProteinHetionet hetionet:interacts:23062-23166Inferred only
GGA3 interacts with STAB1ProteinHetionet hetionet:interacts:23163-23166Inferred only
ORC5 interacts with STAB1ProteinHetionet hetionet:interacts:23166-5001Inferred only
PIK3R2 interacts with STAB1ProteinHetionet hetionet:interacts:23166-5296Inferred only
STAB1 participates in Binding and Uptake of Ligands by Scavenger ReceptorsPathwayReactome R-HSA-2173782Inferred only
STAB1 participates in Scavenging by Class H ReceptorsPathwayReactome R-HSA-3000497Inferred only
STAB1 participates in Vesicle-mediated transportPathwayReactome R-HSA-5653656Inferred only
STAB1 regulates negative regulation of angiogenesisBiological processgene ontology Q9NY15|GO:0016525Inferred only

Other names

5 names

Resolves to: STAB1

Also called: Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1FEEL-1FEEL1KIAA0246MS-1 antigen

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