Proteins/UNIPROT:Q9H5V9

STEEP1

ProteinUNIPROT:Q9H5V9

Molecular adapter that stimulates membrane curvature formation and subsequent endoplasmic reticulum exit site (ERES) establishment by recruiting PI3K complex I, leading to COPII vesicle-mediated transport. Promotes endoplasmic reticulum (ER) exit of cGAMP-activated STING1 oligomers..

Function from UniProtKB (Q9H5V9), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

1 row

intellectual disability, X-linked 107 has a germline basis in STEEP1DiseaseGenCC HGNC:26239|MONDO:0049222Inferred only

Statements

19 statements

19 statements · 2 reference databases · Subject: STEEP1 · Sources: Hetionet, Reactome

Order

STEEP1 covaries with BIN2ProteinHetionet hetionet:covaries:51411-63932Inferred only
C2orf81 covaries with STEEP1ProteinHetionet hetionet:covaries:388963-63932Inferred only
STEEP1 covaries with CENPUProteinHetionet hetionet:covaries:63932-79682Inferred only
STEEP1 covaries with IGF2BP3ProteinHetionet hetionet:covaries:10643-63932Inferred only
STEEP1 covaries with LRRC14ProteinHetionet hetionet:covaries:63932-9684Inferred only
STEEP1 covaries with OR6S1ProteinHetionet hetionet:covaries:341799-63932Inferred only
STEEP1 covaries with PIK3R1ProteinHetionet hetionet:covaries:5295-63932Inferred only
STEEP1 covaries with RAVER1ProteinHetionet hetionet:covaries:125950-63932Inferred only
STEEP1 covaries with STAB1ProteinHetionet hetionet:covaries:23166-63932Inferred only
STEEP1 covaries with VEGFBProteinHetionet hetionet:covaries:63932-7423Inferred only
APP interacts with STEEP1ProteinHetionet hetionet:interacts:351-63932Inferred only
NFKBIL1 interacts with STEEP1ProteinHetionet hetionet:interacts:4795-63932Inferred only

Show the remaining 7

RBM4 interacts with STEEP1ProteinHetionet hetionet:interacts:5936-63932Inferred only
SNW1 interacts with STEEP1ProteinHetionet hetionet:interacts:22938-63932Inferred only
UBC interacts with STEEP1ProteinHetionet hetionet:interacts:63932-7316Inferred only
STEEP1 participates in Metabolism of RNAPathwayReactome R-HSA-8953854Inferred only
STEEP1 participates in mRNA SplicingPathwayReactome R-HSA-72172Inferred only
STEEP1 participates in mRNA Splicing - Major PathwayPathwayReactome R-HSA-72163Inferred only
STEEP1 participates in Processing of Capped Intron-Containing Pre-mRNAPathwayReactome R-HSA-72203Inferred only

Other names

3 names

Resolves to: STEEP1

Also called: CXorf56STEEPSTING ER exit protein

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