Proteins/UNIPROT:Q16629

SRSF7

ProteinUNIPROT:Q16629

Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon 10. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway); enhances NXF1-NXT1 RNA-binding activity. RNA-binding is semi-sequence specific..

Function from UniProtKB (Q16629), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

52 statements

52 statements · 4 reference databases · Subject: SRSF7 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

Order

COPS7B covaries with SRSF7ProteinHetionet hetionet:covaries:6432-64708Inferred only
SRSF7 covaries with EIF4A3ProteinHetionet hetionet:covaries:6432-9775Inferred only
LSM6 covaries with SRSF7ProteinHetionet hetionet:covaries:11157-6432Inferred only
SRSF7 covaries with RNF166ProteinHetionet hetionet:covaries:115992-6432Inferred only
SRSF7 covaries with SART1ProteinHetionet hetionet:covaries:6432-9092Inferred only
SRSF7 covaries with VAMP3ProteinHetionet hetionet:covaries:6432-9341Inferred only
SRSF7 covaries with ZNF524ProteinHetionet hetionet:covaries:147807-6432Inferred only
BARD1 interacts with SRSF7ProteinHetionet hetionet:interacts:580-6432Inferred only
SRSF7 interacts with CAND1ProteinHetionet hetionet:interacts:55832-6432Inferred only
SRSF7 interacts with CCNL2ProteinHetionet hetionet:interacts:6432-81669Inferred only
SRSF7 interacts with CDK19ProteinHetionet hetionet:interacts:23097-6432Inferred only
CDK2 interacts with SRSF7ProteinHetionet hetionet:interacts:1017-6432Inferred only

Show the remaining 40

CDK6 interacts with SRSF7ProteinHetionet hetionet:interacts:1021-6432Inferred only
SRSF7 interacts with COPS5ProteinHetionet hetionet:interacts:10987-6432Inferred only
SRSF7 interacts with CPSF6ProteinHetionet hetionet:interacts:11052-6432Inferred only
SRSF7 interacts with CUL1ProteinHetionet hetionet:interacts:6432-8454Inferred only
SRSF7 interacts with CUL2ProteinHetionet hetionet:interacts:6432-8453Inferred only
SRSF7 interacts with CUL5ProteinHetionet hetionet:interacts:6432-8065Inferred only
SRSF7 interacts with DUSP11ProteinHetionet hetionet:interacts:6432-8446Inferred only
SRSF7 interacts with EIF4A3ProteinHetionet hetionet:interacts:6432-9775Inferred only
ESR1 interacts with SRSF7ProteinHetionet hetionet:interacts:2099-6432Inferred only
HDGF interacts with SRSF7ProteinHetionet hetionet:interacts:3068-6432Inferred only
MAGOH interacts with SRSF7ProteinHetionet hetionet:interacts:4116-6432Inferred only
NEDD8 interacts with SRSF7ProteinHetionet hetionet:interacts:4738-6432Inferred only
SRSF7 interacts with NXF1ProteinHetionet hetionet:interacts:10482-6432Inferred only
SRSF7 interacts with PAXIP1ProteinHetionet hetionet:interacts:22976-6432Inferred only
PCBP2 interacts with SRSF7ProteinHetionet hetionet:interacts:5094-6432Inferred only
SRSF7 interacts with PCLAFProteinHetionet hetionet:interacts:6432-9768Inferred only
RBBP6 interacts with SRSF7ProteinHetionet hetionet:interacts:5930-6432Inferred only
SRSF7 interacts with SREK1ProteinHetionet hetionet:interacts:140890-6432Inferred only
SRSF7 interacts with SRPK1ProteinHetionet hetionet:interacts:6432-6732Inferred only
SRSF7 interacts with SRPK2ProteinHetionet hetionet:interacts:6432-6733Inferred only
SRSF7 interacts with UBCProteinHetionet hetionet:interacts:6432-7316Inferred only
SRSF7 participates in Dengue Virus InfectionPathwayReactome R-HSA-9839923Inferred only
SRSF7 participates in Dengue Virus-Host InteractionsPathwayReactome R-HSA-9918481Inferred only
SRSF7 participates in DiseasePathwayReactome R-HSA-1643685Inferred only
SRSF7 participates in Infectious diseasePathwayReactome R-HSA-5663205Inferred only
SRSF7 participates in Metabolism of RNAPathwayReactome R-HSA-8953854Inferred only
SRSF7 participates in mRNA 3'-end processingPathwayReactome R-HSA-72187Inferred only
SRSF7 participates in mRNA PolyadenylationPathwayReactome R-HSA-9770562Inferred only
SRSF7 participates in mRNA processingPathwayWikiPathways WP411Inferred only
SRSF7 participates in mRNA SplicingPathwayReactome R-HSA-72172Inferred only
SRSF7 participates in mRNA Splicing - Major PathwayPathwayReactome R-HSA-72163Inferred only
SRSF7 participates in mRNA Splicing - Minor PathwayPathwayReactome R-HSA-72165Inferred only
SRSF7 participates in Processing of Capped Intron-Containing Pre-mRNAPathwayReactome R-HSA-72203Inferred only
SRSF7 participates in Transport of Mature mRNA derived from an Intron-Containing TranscriptPathwayReactome R-HSA-159236Inferred only
SRSF7 participates in Transport of Mature Transcript to CytoplasmPathwayReactome R-HSA-72202Inferred only
SRSF7 participates in Viral Infection PathwaysPathwayReactome R-HSA-9824446Inferred only
SRSF7 regulates negative regulation of mRNA splicing, via spliceosomeBiological processgene ontology Q16629|GO:0048025Inferred only
SRSF7 regulates regulation of alternative mRNA splicing, via spliceosomeBiological processgene ontology Q16629|GO:0000381Inferred only
CDX2 decreases the expression of SRSF7ProteinHetionet hetionet:regulates:1045-6432Inferred only
HERPUD1 decreases the expression of SRSF7ProteinHetionet hetionet:regulates:9709-6432Inferred only

Other names

3 names

Resolves to: SRSF7

Also called: SFRS7Splicing factor 9G8Splicing factor, arginine/serine-rich 7

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