Proteins/UNIPROT:Q3SY56

SP6

ProteinUNIPROT:Q3SY56

Promotes cell proliferation (By similarity). Plays a role in tooth germ growth (By similarity). Plays a role in the control of enamel mineralization. Binds the AMBN promoter..

Function from UniProtKB (Q3SY56), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

1 row

amelogenesis imperfecta, IIa 1K has a germline basis in SP6DiseaseGenCC HGNC:14530|MONDO:0031084Inferred only

Statements

17 statements

17 statements · 2 reference databases · Subject: SP6 · Sources: gene ontology, Hetionet

Order

SP6 covaries with B3GALT6ProteinHetionet hetionet:covaries:126792-80320Inferred only
SP6 covaries with C1QTNF4ProteinHetionet hetionet:covaries:114900-80320Inferred only
DNAJC10 covaries with SP6ProteinHetionet hetionet:covaries:54431-80320Inferred only
EBF4 covaries with SP6ProteinHetionet hetionet:covaries:57593-80320Inferred only
LHX3 covaries with SP6ProteinHetionet hetionet:covaries:8022-80320Inferred only
SP6 covaries with PACS2ProteinHetionet hetionet:covaries:23241-80320Inferred only
PRR3 covaries with SP6ProteinHetionet hetionet:covaries:80320-80742Inferred only
RAP1GAP2 covaries with SP6ProteinHetionet hetionet:covaries:23108-80320Inferred only
SP6 regulates regulation of transcription by RNA polymerase IIBiological processgene ontology Q3SY56|GO:0006357Inferred only
SP6 increases the expression of BAMBIProteinHetionet hetionet:regulates:80320-25805Inferred only
SP6 decreases the expression of CDC25BProteinHetionet hetionet:regulates:80320-994Inferred only
SP6 increases the expression of CES1ProteinHetionet hetionet:regulates:80320-1066Inferred only

Show the remaining 5

SP6 decreases the expression of FOSL1ProteinHetionet hetionet:regulates:80320-8061Inferred only
SP6 increases the expression of FYNProteinHetionet hetionet:regulates:80320-2534Inferred only
SP6 increases the expression of ICAM1ProteinHetionet hetionet:regulates:80320-3383Inferred only
SP6 increases the expression of LAMA3ProteinHetionet hetionet:regulates:80320-3909Inferred only
SP6 increases the expression of TIAM1ProteinHetionet hetionet:regulates:80320-7074Inferred only

Other names

3 names

Resolves to: SP6

Also called: KLF14Krueppel-like factor 14Transcription factor Sp6

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