Proteins/UNIPROT:Q8TBB6

SLC7A14

ProteinUNIPROT:Q8TBB6Solute carrier family 7 member 14

Imports 4-aminobutanoate (GABA) into lysosomes. May act as a GABA sensor that regulates mTORC2-dependent INS signaling and gluconeogenesis. The transport mechanism and substrate selectivity remain to be elucidated..

Function from UniProtKB (Q8TBB6), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

2 rows

retinitis pigmentosa has a germline basis in SLC7A14DiseaseGenCC HGNC:29326|MONDO:0019200Inferred only
retinitis pigmentosa 68 has a germline basis in SLC7A14DiseaseGenCC HGNC:29326|MONDO:0014323Inferred only

Statements

14 statements

14 statements · 2 reference databases · Subject: SLC7A14 · Sources: Hetionet, Rhea

Order

AQP12B covaries with SLC7A14ProteinHetionet hetionet:covaries:57709-653437Inferred only
SLC7A14 covaries with CA11ProteinHetionet hetionet:covaries:57709-770Inferred only
CCDC85C covaries with SLC7A14ProteinHetionet hetionet:covaries:317762-57709Inferred only
SLC7A14 covaries with EDC3ProteinHetionet hetionet:covaries:57709-80153Inferred only
HOXC12 covaries with SLC7A14ProteinHetionet hetionet:covaries:3228-57709Inferred only
MANSC4 covaries with SLC7A14ProteinHetionet hetionet:covaries:100287284-57709Inferred only
SLC7A14 covaries with NTF4ProteinHetionet hetionet:covaries:4909-57709Inferred only
SLC7A14 covaries with PCBP4ProteinHetionet hetionet:covaries:57060-57709Inferred only
PSAPL1 covaries with SLC7A14ProteinHetionet hetionet:covaries:57709-768239Inferred only
RAB39B covaries with SLC7A14ProteinHetionet hetionet:covaries:116442-57709Inferred only
SLC7A14 covaries with TNPO2ProteinHetionet hetionet:covaries:30000-57709Inferred only
SLC7A14 covaries with WNT7BProteinHetionet hetionet:covaries:57709-7477Inferred only

Show the remaining 2

PPP1CA interacts with SLC7A14ProteinHetionet hetionet:interacts:5499-57709Inferred only
4-aminobutanoate is transported by SLC7A14CompoundRhea RHEA:35035Inferred only

Reactions

1 reaction

4-aminobutanoate4-aminobutanoate
Transported by BEST1 or SLC7A14
Reaction pageRight to leftBalanced
Rhea RHEA:35035CC BY 4.0Reference data

Other names

3 names

Resolves to: SLC7A14

Also called: Gamma-aminobutyric acid transporter SLC7A14KIAA1613Solute carrier family 7 member 14

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