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A reference for what the literature reports. Not medical advice.

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Proteins/UNIPROT:Q9NQ40

SLC52A3

Protein·UNIPROT:Q9NQ40Solute carrier family 52, riboflavin transporter, member 3

Open in the graph

Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism. Humans are unable to synthesize vitamin B2/riboflavin and must obtain it via intestinal absorption..

Function from UniProtKB (Q9NQ40), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

2 rows

Brown-Vialetto-van Laere syndrome 1 has a germline basis in SLC52A3DiseaseGenCC HGNC:16187|MONDO:0024537Inferred only
progressive bulbar palsy has a germline basis in SLC52A3DiseaseGenCC HGNC:16187|MONDO:0008890Inferred only

Statements

6 statements

6 statements · 3 reference databases · Subject: SLC52A3 · Sources: Human-GEM, Reactome, Rhea

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SLC52A3 participates in MetabolismPathwayReactome R-HSA-1430728Inferred only
SLC52A3 participates in Metabolism of vitamins and cofactorsPathwayReactome R-HSA-196854Inferred only
SLC52A3 participates in Metabolism of water-soluble vitamins and cofactorsPathwayReactome R-HSA-196849Inferred only
SLC52A3 participates in Vitamin B2 (riboflavin) metabolismPathwayReactome R-HSA-196843Inferred only
riboflavin is transported by SLC52A3CompoundHuman-GEM MAR08730Inferred only
riboflavin is transported by SLC52A3CompoundRhea RHEA:35015Inferred only

Reactions

2 reactions

ATP+water+riboflavinADP+proton+phosphate(3-)+riboflavin
Transported by SLC52A3
Reaction pageLeft to rightBalancedcytosol, extracellular space
Human-GEM MAR08730CC BY 4.0Reference data
riboflavinriboflavin
Transported by SLC52A2 or SLC52A3 or SLC52A1

Other names

5 names

Resolves to: SLC52A3

Also called: C20orf54hRFT2RFT2RFVT3Riboflavin transporter 2

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Reaction pageDirection not assertedBalanced

Rhea RHEA:35015CC BY 4.0Reference data