Proteins/UNIPROT:P29508

SERPINB3

ProteinUNIPROT:P29508

May act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. Also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1)..

Function from UniProtKB (P29508), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

14 statements

14 statements · 3 reference databases · Subject: SERPINB3 · Sources: Hetionet, Reactome, WikiPathways

Order

SERPINB3 interacts with COPS5ProteinHetionet hetionet:interacts:10987-6317Inferred only
CTSK interacts with SERPINB3ProteinHetionet hetionet:interacts:1513-6317Inferred only
CTSL interacts with SERPINB3ProteinHetionet hetionet:interacts:1514-6317Inferred only
CTSS interacts with SERPINB3ProteinHetionet hetionet:interacts:1520-6317Inferred only
SERPINB3 interacts with CUL2ProteinHetionet hetionet:interacts:6317-8453Inferred only
MAPK8 interacts with SERPINB3ProteinHetionet hetionet:interacts:5599-6317Inferred only
SERPINB3 interacts with UBCProteinHetionet hetionet:interacts:6317-7316Inferred only
SERPINB3 interacts with UCHL5ProteinHetionet hetionet:interacts:51377-6317Inferred only
SERPINB3 participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
SERPINB3 participates in Innate Immune SystemPathwayReactome R-HSA-168249Inferred only
SERPINB3 participates in Neutrophil degranulationPathwayReactome R-HSA-6798695Inferred only
SERPINB3 participates in Pancreatic cancer subtypesPathwayWikiPathways WP5390Inferred only

Show the remaining 2

MTF2 increases the expression of SERPINB3ProteinHetionet hetionet:regulates:22823-6317Inferred only
RAD23B decreases the expression of SERPINB3ProteinHetionet hetionet:regulates:5887-6317Inferred only

Other names

6 names

Resolves to: SERPINB3

Also called: Protein T4-ASCCASCCA-1SCCA1Squamous cell carcinoma antigen 1T4-A

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