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Proteins/UNIPROT:O75396

SEC22B

Protein·UNIPROT:O75396

Open in the graph

SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER..

Function from UniProtKB (O75396), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

35 statements

35 statements · 3 reference databases · Subject: SEC22B · Sources: gene ontology, Hetionet, Reactome

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HOXC13 covaries with SEC22BProteinHetionet hetionet:covaries:3229-9554Inferred only
IFFO1 covaries with SEC22BProteinHetionet hetionet:covaries:25900-9554Inferred only
MAGEE2 covaries with SEC22BProteinHetionet hetionet:covaries:139599-9554Inferred only
SFT2D3 covaries with SEC22BProteinHetionet hetionet:covaries:84826-9554Inferred only
TUBA3E covaries with SEC22BProteinHetionet hetionet:covaries:112714-9554Inferred only
SEC22B interacts with B3GAT3ProteinHetionet hetionet:interacts:26229-9554Inferred only
ESR1 interacts with SEC22BProteinHetionet hetionet:interacts:2099-9554Inferred only
STX5 interacts with SEC22BProteinHetionet hetionet:interacts:6811-9554Inferred only
SUMO2 interacts with SEC22BProteinHetionet hetionet:interacts:6613-9554Inferred only
UBC interacts with SEC22BProteinHetionet hetionet:interacts:7316-9554Inferred only
UBL4A interacts with SEC22BProteinHetionet hetionet:interacts:8266-9554Inferred only
VCP interacts with SEC22BProteinHetionet hetionet:interacts:7415-9554Inferred only

Show the remaining 23

SEC22B participates in Adaptive Immune SystemPathwayReactome R-HSA-1280218Inferred only
SEC22B participates in Antigen processing-Cross presentationPathwayReactome R-HSA-1236975Inferred only
SEC22B participates in Asparagine N-linked glycosylationPathwayReactome R-HSA-446203Inferred only
SEC22B participates in Cargo concentration in the ERPathwayReactome R-HSA-5694530Inferred only
SEC22B participates in Class I MHC mediated antigen processing & presentationPathwayReactome R-HSA-983169Inferred only
SEC22B participates in COPI-dependent Golgi-to-ER retrograde trafficPathwayReactome R-HSA-6811434Inferred only
SEC22B participates in COPII-mediated vesicle transportPathwayReactome R-HSA-204005Inferred only
SEC22B participates in ER to Golgi Anterograde TransportPathwayReactome R-HSA-199977Inferred only
SEC22B participates in ER-Phagosome pathwayPathwayReactome R-HSA-1236974Inferred only
SEC22B participates in Golgi-to-ER retrograde transportPathwayReactome R-HSA-8856688Inferred only
SEC22B participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
SEC22B participates in Intra-Golgi and retrograde Golgi-to-ER trafficPathwayReactome R-HSA-6811442Inferred only
SEC22B participates in Membrane TraffickingPathwayReactome R-HSA-199991Inferred only
SEC22B participates in Metabolism of proteinsPathwayReactome R-HSA-392499Inferred only
SEC22B participates in Post-translational protein modificationPathwayReactome R-HSA-597592Inferred only
SEC22B participates in Transport to the Golgi and subsequent modificationPathwayReactome R-HSA-948021Inferred only
SEC22B participates in Vesicle-mediated transportPathwayReactome R-HSA-5653656Inferred only
SEC22B regulates negative regulation of autophagosome assemblyBiological processgene ontology O75396|GO:1902902Inferred only
SEC22B regulates positive regulation of protein catabolic processBiological processgene ontology O75396|GO:0045732Inferred only
ALDH7A1 increases the expression of SEC22BProteinHetionet hetionet:regulates:501-9554Inferred only
ANKRD49 decreases the expression of SEC22BProteinHetionet hetionet:regulates:54851-9554Inferred only
CD58 decreases the expression of SEC22BProteinHetionet hetionet:regulates:965-9554Inferred only
HDAC2 increases the expression of SEC22BProteinHetionet hetionet:regulates:3066-9554Inferred only

Other names

6 names

Resolves to: SEC22B

Also called: ER-Golgi SNARE of 24 kDaERS-24ERS24SEC22 vesicle-trafficking protein homolog BSEC22 vesicle-trafficking protein-like 1SEC22L1

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