Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Proteins/UNIPROT:P13521

SCG2

Protein·UNIPROT:P13521

Open in the graph

Neuroendocrine protein of the granin family that regulates the biogenesis of secretory granules..

Function from UniProtKB (P13521), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

22 statements

22 statements · 3 reference databases · Subject: SCG2 · Sources: gene ontology, Hetionet, Reactome

Search this listOrder

CCSER1 covaries with SCG2ProteinHetionet hetionet:covaries:401145-7857Inferred only
SCG2 covaries with FBN3ProteinHetionet hetionet:covaries:7857-84467Inferred only
GIGYF1 covaries with SCG2ProteinHetionet hetionet:covaries:64599-7857Inferred only
SCG2 covaries with MFRPProteinHetionet hetionet:covaries:7857-83552Inferred only
SCG2 covaries with RAX2ProteinHetionet hetionet:covaries:7857-84839Inferred only
SCG2 interacts with COPS6ProteinHetionet hetionet:interacts:10980-7857Inferred only
SCG2 interacts with PCLAFProteinHetionet hetionet:interacts:7857-9768Inferred only
PIK3R1 interacts with SCG2ProteinHetionet hetionet:interacts:5295-7857Inferred only
SCG2 interacts with SCHIP1ProteinHetionet hetionet:interacts:29970-7857Inferred only
TNF interacts with SCG2ProteinHetionet hetionet:interacts:7124-7857Inferred only
SCG2 interacts with TUBB4BProteinHetionet hetionet:interacts:10383-7857Inferred only
UBC interacts with SCG2ProteinHetionet hetionet:interacts:7316-7857Inferred only

Show the remaining 10

SCG2 interacts with UBQLN1ProteinHetionet hetionet:interacts:29979-7857Inferred only
SCG2 interacts with UBQLN4ProteinHetionet hetionet:interacts:56893-7857Inferred only
SCG2 participates in Metabolism of proteinsPathwayReactome R-HSA-392499Inferred only
SCG2 participates in Post-translational protein modificationPathwayReactome R-HSA-597592Inferred only
SCG2 participates in Post-translational protein phosphorylationPathwayReactome R-HSA-8957275Inferred only
SCG2 participates in Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)PathwayReactome R-HSA-381426Inferred only
SCG2 regulates negative regulation of endothelial cell apoptotic processBiological processgene ontology P13521|GO:2000352Inferred only
SCG2 regulates negative regulation of endothelial cell proliferationBiological processgene ontology P13521|GO:0001937Inferred only
SCG2 regulates negative regulation of extrinsic apoptotic signaling pathwayBiological processgene ontology P13521|GO:2001237Inferred only
SCG2 regulates positive regulation of endothelial cell proliferationBiological processgene ontology P13521|GO:0001938Inferred only

Other names

6 names

Resolves to: SCG2

Also called: [Cleaved into: SecretoneurinCHGCChromogranin-CSecretogranin IISgIISN

← Every protein Find it in the graph →