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Proteins/UNIPROT:Q9H2S5
Plays an inhibitory role in anti-RNA viral innate immunity by targeting the adapter DDX3X and promoting its 'Lys-48'-linked polyubiquitination. Alternatively, enhances the cGAS-STING pathway activation by promoting 'Lys-63'-linked ubiquitination of STING1, facilitating the STING1-TBK1 complex formation and STING1 activation..
(Microbial infection) Plays a positive role in human immunodeficiency virus (HIV-1) replication..
Function from UniProtKB (Q9H2S5), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
14 statements
14 statements · 2 reference databases · Subject: RNF39 · Sources: gene ontology, Hetionet
2 names
Resolves to: RNF39