Proteins/UNIPROT:P04090

RLN2

ProteinUNIPROT:P04090

Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix.

Function from UniProtKB (P04090), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

15 statements

15 statements · 3 reference databases · Subject: RLN2 · Sources: gene ontology, Hetionet, Reactome

Order

RLN2 covaries with ADAM15ProteinHetionet hetionet:covaries:6019-8751Inferred only
MRPL50 covaries with RLN2ProteinHetionet hetionet:covaries:54534-6019Inferred only
RLN2 interacts with RXFP1ProteinHetionet hetionet:interacts:59350-6019Inferred only
RLN2 interacts with RXFP2ProteinHetionet hetionet:interacts:122042-6019Inferred only
RLN2 participates in Class A/1 (Rhodopsin-like receptors)PathwayReactome R-HSA-373076Inferred only
RLN2 participates in G alpha (s) signalling eventsPathwayReactome R-HSA-418555Inferred only
RLN2 participates in GPCR downstream signallingPathwayReactome R-HSA-388396Inferred only
RLN2 participates in GPCR ligand bindingPathwayReactome R-HSA-500792Inferred only
RLN2 participates in Peptide ligand-binding receptorsPathwayReactome R-HSA-375276Inferred only
RLN2 participates in Relaxin receptorsPathwayReactome R-HSA-444821Inferred only
RLN2 participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
RLN2 participates in Signaling by GPCRPathwayReactome R-HSA-372790Inferred only

Show the remaining 3

RLN2 regulates positive regulation of angiogenesisBiological processgene ontology P04090|GO:0045766Inferred only
RLN2 regulates positive regulation of gene expressionBiological processgene ontology P04090|GO:0010628Inferred only
RLN2 regulates regulation of catalytic activityBiological processgene ontology P04090|GO:0050790Inferred only

Other names

1 name

Resolves to: RLN2

Also called: Prorelaxin H2 [Cleaved into: Relaxin B chain; Relaxin A chain]

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