Proteins/UNIPROT:Q9HBX9

RXFP1

ProteinUNIPROT:Q9HBX9

Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP.

Function from UniProtKB (Q9HBX9), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

24 statements

24 statements · 3 reference databases · Subject: RXFP1 · Sources: Hetionet, Reactome, WikiPathways

Order

AKAP5 interacts with RXFP1ProteinHetionet hetionet:interacts:59350-9495Inferred only
RLN1 interacts with RXFP1ProteinHetionet hetionet:interacts:59350-6013Inferred only
RLN2 interacts with RXFP1ProteinHetionet hetionet:interacts:59350-6019Inferred only
RXFP1 participates in Class A/1 (Rhodopsin-like receptors)PathwayReactome R-HSA-373076Inferred only
RXFP1 participates in G alpha (s) signalling eventsPathwayReactome R-HSA-418555Inferred only
RXFP1 participates in GPCR downstream signallingPathwayReactome R-HSA-388396Inferred only
RXFP1 participates in GPCR ligand bindingPathwayReactome R-HSA-500792Inferred only
RXFP1 participates in GPCRs otherPathwayWikiPathways WP117Inferred only
RXFP1 participates in Myometrial relaxation and contraction pathwaysPathwayWikiPathways WP289Inferred only
RXFP1 participates in Peptide ligand-binding receptorsPathwayReactome R-HSA-375276Inferred only
RXFP1 participates in Relaxin receptorsPathwayReactome R-HSA-444821Inferred only
RXFP1 participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only

Show the remaining 12

RXFP1 participates in Signaling by GPCRPathwayReactome R-HSA-372790Inferred only
RXFP1 increases the expression of BNIP3ProteinHetionet hetionet:regulates:59350-664Inferred only
RXFP1 decreases the expression of CAPN2ProteinHetionet hetionet:regulates:59350-824Inferred only
RXFP1 increases the expression of CCDC92ProteinHetionet hetionet:regulates:59350-80212Inferred only
RXFP1 decreases the expression of CDC25BProteinHetionet hetionet:regulates:59350-994Inferred only
RXFP1 decreases the expression of LGALS1ProteinHetionet hetionet:regulates:59350-3956Inferred only
RXFP1 increases the expression of MALProteinHetionet hetionet:regulates:59350-4118Inferred only
RXFP1 increases the expression of MCOLN1ProteinHetionet hetionet:regulates:59350-57192Inferred only
RXFP1 increases the expression of NFIL3ProteinHetionet hetionet:regulates:59350-4783Inferred only
RXFP1 decreases the expression of RHOAProteinHetionet hetionet:regulates:59350-387Inferred only
RXFP1 decreases the expression of RPIAProteinHetionet hetionet:regulates:59350-22934Inferred only
RXFP1 increases the expression of WIF1ProteinHetionet hetionet:regulates:59350-11197Inferred only

Other names

3 names

Resolves to: RXFP1

Also called: Leucine-rich repeat-containing G protein-coupled receptor 7LGR7Relaxin family peptide receptor 1

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