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Proteins/UNIPROT:Q9H4X1

RGCC

Protein·UNIPROT:Q9H4X1

Open in the graph

Modulates the activity of cell cycle-specific kinases. Enhances CDK1 activity. May contribute to the regulation of the cell cycle. May inhibit growth of glioma cells by promoting arrest of mitotic progression at the G2/M transition. Fibrogenic factor contributing to the pathogenesis of renal fibrosis through fibroblast activation..

Function from UniProtKB (Q9H4X1), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

30 statements

30 statements · 3 reference databases · Subject: RGCC · Sources: gene ontology, Hetionet, Reactome

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CDK1 interacts with RGCCProteinHetionet hetionet:interacts:28984-983Inferred only
SMAD2 interacts with RGCCProteinHetionet hetionet:interacts:28984-4087Inferred only
SMAD3 interacts with RGCCProteinHetionet hetionet:interacts:28984-4088Inferred only
RGCC participates in Gene expression (Transcription)PathwayReactome R-HSA-74160Inferred only
RGCC participates in Generic Transcription PathwayPathwayReactome R-HSA-212436Inferred only
RGCC participates in RNA Polymerase II TranscriptionPathwayReactome R-HSA-73857Inferred only
RGCC participates in TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertainPathwayReactome R-HSA-6804115Inferred only
RGCC participates in TP53 Regulates Transcription of Cell Cycle GenesPathwayReactome R-HSA-6791312Inferred only
RGCC participates in Transcriptional Regulation by TP53PathwayReactome R-HSA-3700989Inferred only
RGCC regulates negative regulation of angiogenesisBiological processgene ontology Q9H4X1|GO:0016525Inferred only
RGCC regulates negative regulation of blood vessel endothelial cell migrationBiological processgene ontology Q9H4X1|GO:0043537Inferred only
RGCC regulates negative regulation of cell population proliferationBiological processgene ontology Q9H4X1|GO:0008285Inferred only

Show the remaining 18

RGCC regulates negative regulation of cell-cell adhesion mediated by cadherinBiological processgene ontology Q9H4X1|GO:2000048Inferred only
RGCC regulates negative regulation of cytokine productionBiological processgene ontology Q9H4X1|GO:0001818Inferred only
RGCC regulates negative regulation of endothelial cell proliferationBiological processgene ontology Q9H4X1|GO:0001937Inferred only
RGCC regulates negative regulation of exit from mitosisBiological processgene ontology Q9H4X1|GO:0001100Inferred only
RGCC regulates negative regulation of fibroblast growth factor productionBiological processgene ontology Q9H4X1|GO:0090272Inferred only
RGCC regulates negative regulation of mitotic cell cycle phase transitionBiological processgene ontology Q9H4X1|GO:1901991Inferred only
RGCC regulates positive regulation of collagen biosynthetic processBiological processgene ontology Q9H4X1|GO:0032967Inferred only
RGCC regulates positive regulation of cytokine productionBiological processgene ontology Q9H4X1|GO:0001819Inferred only
RGCC regulates positive regulation of endothelial cell apoptotic processBiological processgene ontology Q9H4X1|GO:2000353Inferred only
RGCC regulates positive regulation of epithelial to mesenchymal transitionBiological processgene ontology Q9H4X1|GO:0010718Inferred only
RGCC regulates positive regulation of extracellular matrix assemblyBiological processgene ontology Q9H4X1|GO:1901203Inferred only
RGCC regulates positive regulation of extracellular matrix constituent secretionBiological processgene ontology Q9H4X1|GO:0003331Inferred only
RGCC regulates positive regulation of G1/S transition of mitotic cell cycleBiological processgene ontology Q9H4X1|GO:1900087Inferred only
RGCC regulates positive regulation of gene expressionBiological processgene ontology Q9H4X1|GO:0010628Inferred only
RGCC regulates positive regulation of mitotic cell cycleBiological processgene ontology Q9H4X1|GO:0045931Inferred only
RGCC regulates positive regulation of stress fiber assemblyBiological processgene ontology Q9H4X1|GO:0051496Inferred only
RGCC regulates positive regulation of transcription by RNA polymerase IIBiological processgene ontology Q9H4X1|GO:0045944Inferred only
RGCC regulates positive regulation of vascular associated smooth muscle cell proliferationBiological processgene ontology Q9H4X1|GO:1904707Inferred only

Other names

4 names

Resolves to: RGCC

Also called: C13orf15Response gene to complement 32 proteinRGC-32RGC32

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