Proteins/UNIPROT:Q99575

POP1

ProteinUNIPROT:Q99575

Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences..

Function from UniProtKB (Q99575), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

2 rows

anauxetic dysplasia has a germline basis in POP1DiseaseGenCC HGNC:30129|MONDO:0011773Inferred only
anauxetic dysplasia 2 has a germline basis in POP1DiseaseGenCC HGNC:30129|MONDO:0054561Inferred only

Statements

25 statements

25 statements · 2 reference databases · Subject: POP1 · Sources: Hetionet, Reactome

Order

POP1 interacts with CAND1ProteinHetionet hetionet:interacts:10940-55832Inferred only
POP1 interacts with COPS5ProteinHetionet hetionet:interacts:10940-10987Inferred only
CUL1 interacts with POP1ProteinHetionet hetionet:interacts:10940-8454Inferred only
CUL3 interacts with POP1ProteinHetionet hetionet:interacts:10940-8452Inferred only
ESR1 interacts with POP1ProteinHetionet hetionet:interacts:10940-2099Inferred only
NEDD8 interacts with POP1ProteinHetionet hetionet:interacts:10940-4738Inferred only
PCLAF interacts with POP1ProteinHetionet hetionet:interacts:10940-9768Inferred only
POP4 interacts with POP1ProteinHetionet hetionet:interacts:10775-10940Inferred only
POP1 interacts with POP5ProteinHetionet hetionet:interacts:10940-51367Inferred only
POP1 interacts with RPP25ProteinHetionet hetionet:interacts:10940-54913Inferred only
RPP30 interacts with POP1ProteinHetionet hetionet:interacts:10556-10940Inferred only
RPP38 interacts with POP1ProteinHetionet hetionet:interacts:10557-10940Inferred only

Show the remaining 13

RPP40 interacts with POP1ProteinHetionet hetionet:interacts:10799-10940Inferred only
POP1 interacts with SIRT7ProteinHetionet hetionet:interacts:10940-51547Inferred only
SUMO2 interacts with POP1ProteinHetionet hetionet:interacts:10940-6613Inferred only
UBC interacts with POP1ProteinHetionet hetionet:interacts:10940-7316Inferred only
POP1 participates in Metabolism of RNAPathwayReactome R-HSA-8953854Inferred only
POP1 participates in tRNA processingPathwayReactome R-HSA-72306Inferred only
POP1 participates in tRNA processing in the nucleusPathwayReactome R-HSA-6784531Inferred only
DECR1 decreases the expression of POP1ProteinHetionet hetionet:regulates:1666-10940Inferred only
DMTF1 increases the expression of POP1ProteinHetionet hetionet:regulates:9988-10940Inferred only
HOXA5 increases the expression of POP1ProteinHetionet hetionet:regulates:3202-10940Inferred only
NQO1 increases the expression of POP1ProteinHetionet hetionet:regulates:1728-10940Inferred only
PML increases the expression of POP1ProteinHetionet hetionet:regulates:5371-10940Inferred only
TPD52L2 increases the expression of POP1ProteinHetionet hetionet:regulates:7165-10940Inferred only

Other names

3 names

Resolves to: POP1

Also called: hPOP1KIAA0061Ribonucleases P/MRP protein subunit POP1

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