Proteins/UNIPROT:Q9GZU2

PEG3

ProteinUNIPROT:Q9GZU2

Induces apoptosis in cooperation with SIAH1A. Acts as a mediator between p53/TP53 and BAX in a neuronal death pathway that is activated by DNA damage. Acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B (By similarity). Possesses a tumor suppressing activity in glioma cells..

Function from UniProtKB (Q9GZU2), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

9 statements

9 statements · 2 reference databases · Subject: PEG3 · Sources: gene ontology, Hetionet

Order

PEG3 covaries with DDA1ProteinHetionet hetionet:covaries:5178-79016Inferred only
LIMS1 interacts with PEG3ProteinHetionet hetionet:interacts:3987-5178Inferred only
PEG3 interacts with SIAH2ProteinHetionet hetionet:interacts:5178-6478Inferred only
PEG3 interacts with TRAF2ProteinHetionet hetionet:interacts:5178-7186Inferred only
PEG3 interacts with USP7ProteinHetionet hetionet:interacts:5178-7874Inferred only
PEG3 regulates negative regulation of transcription by RNA polymerase IIBiological processgene ontology Q9GZU2|GO:0000122Inferred only
PEG3 regulates positive regulation of transcription by RNA polymerase IIBiological processgene ontology Q9GZU2|GO:0045944Inferred only
PEG3 regulates regulation of gene expressionBiological processgene ontology Q9GZU2|GO:0010468Inferred only
PEG3 regulates regulation of transcription by RNA polymerase IIBiological processgene ontology Q9GZU2|GO:0006357Inferred only

Other names

4 names

Resolves to: PEG3

Also called: KIAA0287Paternally-expressed gene 3 proteinZinc finger and SCAN domain-containing protein 24ZSCAN24

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