Proteins/UNIPROT:Q9BW61

DDA1

ProteinUNIPROT:Q9BW61

Functions as a component of numerous distinct DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. In the DCX complexes, acts as a scaffolding subunit required to stabilize the complex..

Function from UniProtKB (Q9BW61), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

17 statements

17 statements · 3 reference databases · Subject: DDA1 · Sources: gene ontology, Hetionet, Reactome

Order

PEG3 covaries with DDA1ProteinHetionet hetionet:covaries:5178-79016Inferred only
COPS5 interacts with DDA1ProteinHetionet hetionet:interacts:10987-79016Inferred only
COPS6 interacts with DDA1ProteinHetionet hetionet:interacts:10980-79016Inferred only
CUL4A interacts with DDA1ProteinHetionet hetionet:interacts:79016-8451Inferred only
DDB1 interacts with DDA1ProteinHetionet hetionet:interacts:1642-79016Inferred only
UBC interacts with DDA1ProteinHetionet hetionet:interacts:7316-79016Inferred only
DDA1 participates in Metabolism of proteinsPathwayReactome R-HSA-392499Inferred only
DDA1 participates in NeddylationPathwayReactome R-HSA-8951664Inferred only
DDA1 participates in Post-translational protein modificationPathwayReactome R-HSA-597592Inferred only
DDA1 regulates regulation of natural killer cell activationBiological processgene ontology Q9BW61|GO:0032814Inferred only
DDA1 regulates regulation of proteasomal ubiquitin-dependent protein catabolic processBiological processgene ontology Q9BW61|GO:0032434Inferred only
DNTTIP2 increases the expression of DDA1ProteinHetionet hetionet:regulates:30836-79016Inferred only

Show the remaining 5

HEY1 increases the expression of DDA1ProteinHetionet hetionet:regulates:23462-79016Inferred only
NR2F2 increases the expression of DDA1ProteinHetionet hetionet:regulates:7026-79016Inferred only
PLEKHJ1 increases the expression of DDA1ProteinHetionet hetionet:regulates:55111-79016Inferred only
PLPP1 increases the expression of DDA1ProteinHetionet hetionet:regulates:8611-79016Inferred only
RAD23B increases the expression of DDA1ProteinHetionet hetionet:regulates:5887-79016Inferred only

Other names

4 names

Resolves to: DDA1

Also called: C19orf58PCIA-1PCIA1Placenta cross-immune reaction antigen 1

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