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A reference for what the literature reports. Not medical advice.

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Proteins/UNIPROT:Q9UKZ9

PCOLCE2

Protein·UNIPROT:Q9UKZ9

Open in the graph

Binds to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1..

Function from UniProtKB (Q9UKZ9), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

9 statements

9 statements · 2 reference databases · Subject: PCOLCE2 · Sources: Hetionet, Reactome

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PCOLCE2 covaries with KLK1ProteinHetionet hetionet:covaries:26577-3816Inferred only
PCOLCE2 participates in Collagen biosynthesis and modifying enzymesPathwayReactome R-HSA-1650814Inferred only
PCOLCE2 participates in Collagen formationPathwayReactome R-HSA-1474290Inferred only
PCOLCE2 participates in Extracellular matrix organizationPathwayReactome R-HSA-1474244Inferred only
EGR1 decreases the expression of PCOLCE2ProteinHetionet hetionet:regulates:1958-26577Inferred only
GNAI2 decreases the expression of PCOLCE2ProteinHetionet hetionet:regulates:2771-26577Inferred only
GNAS decreases the expression of PCOLCE2ProteinHetionet hetionet:regulates:2778-26577Inferred only
HADH decreases the expression of PCOLCE2ProteinHetionet hetionet:regulates:3033-26577Inferred only
SLC9A1 decreases the expression of PCOLCE2ProteinHetionet hetionet:regulates:6548-26577Inferred only

Other names

4 names

Resolves to: PCOLCE2

Also called: PCPE-2PCPE2Procollagen C-proteinase enhancer 2Procollagen COOH-terminal proteinase enhancer 2

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