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Proteins/UNIPROT:P0C6T2
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. Specifically involved in maintaining stability of STT3A-containing OST complexes..
Function from UniProtKB (P0C6T2), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
39 statements
39 statements · 2 reference databases · Subject: OST4 · Sources: Hetionet, Reactome
1 name
Resolves to: OST4