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Proteins/UNIPROT:Q9BXW6

OSBPL1A

Protein·UNIPROT:Q9BXW6

Open in the graph

Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate (By similarity). Stabilizes GTP-bound RAB7A on late endosomes/lysosomes and alters functional properties of late endocytic compartments via its interaction with RAB7A. Binds 25-hydroxycholesterol and cholesterol..

Function from UniProtKB (Q9BXW6), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

14 statements

14 statements · 2 reference databases · Subject: OSBPL1A · Sources: Hetionet, Reactome

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ZNF792 covaries with OSBPL1AProteinHetionet hetionet:covaries:114876-126375Inferred only
UBC interacts with OSBPL1AProteinHetionet hetionet:interacts:114876-7316Inferred only
OSBPL1A participates in Adaptive Immune SystemPathwayReactome R-HSA-1280218Inferred only
OSBPL1A participates in Affinity selection of immunoglobulinsPathwayReactome R-HSA-9938027Inferred only
OSBPL1A participates in Bile acid and bile salt metabolismPathwayReactome R-HSA-194068Inferred only
OSBPL1A participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
OSBPL1A participates in Immunoglobulin maturationPathwayReactome R-HSA-9938026Inferred only
OSBPL1A participates in MetabolismPathwayReactome R-HSA-1430728Inferred only
OSBPL1A participates in Metabolism of lipidsPathwayReactome R-HSA-556833Inferred only
OSBPL1A participates in Metabolism of steroidsPathwayReactome R-HSA-8957322Inferred only
OSBPL1A participates in MHC class II antigen presentationPathwayReactome R-HSA-2132295Inferred only
OSBPL1A participates in Processing of antigen in germinal center B cellsPathwayReactome R-HSA-9979719Inferred only

Show the remaining 2

OSBPL1A participates in Synthesis of bile acids and bile saltsPathwayReactome R-HSA-192105Inferred only
SGCB decreases the expression of OSBPL1AProteinHetionet hetionet:regulates:6443-114876Inferred only

Other names

6 names

Resolves to: OSBPL1A

Also called: ORP-1ORP1OSBP-related protein 1OSBP8OSBPL1OSBPL1B

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