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Proteins/UNIPROT:Q9ULD0
2-oxoglutarate dehydrogenase (E1-like) component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDHC) which mediates the decarboxylation of alpha-ketoglutarate in the tricarboxylic acid cycle. The OGDHC complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) while reducing NAD(+) to NADH (By similarity). The OGDHC complex is mainly active in the mitochondrion (By similarity). Involved in the inhibition of cell proliferation and in apoptosis..
Function from UniProtKB (Q9ULD0), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
12 statements
12 statements · 3 reference databases · Subject: OGDHL · Sources: Hetionet, UniProt, WikiPathways
1 reaction
N(6)-[(R)-lipoyl]-L-lysyl-[protein]+2-oxoglutarate(2-)+hydronN(6)-[(R)-S(8)-succinyldihydrolipoyl]-L-lysyl-[protein]+carbon dioxide
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:12188CC BY 4.0Reference data
4 names
Resolves to: OGDHL