Proteins/UNIPROT:P53384

NUBP1

ProteinUNIPROT:P53384

Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication (By similarity). Negatively regulates cilium formation and structure (By similarity)..

Function from UniProtKB (P53384), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

11 statements

11 statements · 5 reference databases · Subject: NUBP1 · Sources: gene ontology, Hetionet, Reactome, UniProt, WikiPathways

Order

CETP covaries with NUBP1ProteinHetionet hetionet:covaries:1071-4682Inferred only
NUBP1 interacts with NDNProteinHetionet hetionet:interacts:4682-4692Inferred only
NUBP1 interacts with SPRY2ProteinHetionet hetionet:interacts:10253-4682Inferred only
NUBP1 interacts with UBCProteinHetionet hetionet:interacts:4682-7316Inferred only
NUBP1 participates in Cytosolic iron-sulfur cluster assemblyPathwayReactome R-HSA-2564830Inferred only
NUBP1 participates in Iron sulfur cluster biogenesisPathwayWikiPathways WP5152Inferred only
NUBP1 participates in MetabolismPathwayReactome R-HSA-1430728Inferred only
NUBP1 regulates regulation of cell growthBiological processgene ontology P53384|GO:0001558Inferred only
HSPA8 decreases the expression of NUBP1ProteinHetionet hetionet:regulates:3312-4682Inferred only
RPL7 increases the expression of NUBP1ProteinHetionet hetionet:regulates:6129-4682Inferred only
NUBP1 requires the cofactor tetra-mu3-sulfido-tetraironCompoundUniProt P53384Inferred only

Other names

4 names

Resolves to: NUBP1

Also called: NBPNBP 1NBP1Nucleotide-binding protein 1

← Every protein Find it in the graph →