Proteins/UNIPROT:P20929

NEB

ProteinUNIPROT:P20929

This giant muscle protein may be involved in maintaining the structural integrity of sarcomeres and the membrane system associated with the myofibrils. Binds and stabilize F-actin.

Function from UniProtKB (P20929), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

7 rows

autosomal dominant nebulin-related myopathy has a germline basis in NEBDiseaseGenCC HGNC:7720|MONDO:1010152Inferred only
childhood-onset nemaline myopathy has a germline basis in NEBDiseaseGenCC HGNC:7720|MONDO:0015738Inferred only
intermediate nemaline myopathy has a germline basis in NEBDiseaseGenCC HGNC:7720|MONDO:0015736Inferred only
lethal multiple pterygium syndrome has a germline basis in NEBDiseaseGenCC HGNC:7720|MONDO:0009668Inferred only
nemaline myopathy 2 has a germline basis in NEBDiseaseGenCC HGNC:7720|MONDO:0009725Inferred only
severe congenital nemaline myopathy has a germline basis in NEBDiseaseGenCC HGNC:7720|MONDO:0015735Inferred only
typical nemaline myopathy has a germline basis in NEBDiseaseGenCC HGNC:7720|MONDO:0015737Inferred only

Statements

28 statements

28 statements · 4 reference databases · Subject: NEB · Sources: gene ontology, Hetionet, Reactome, WikiPathways

Order

NEB covaries with CDS2ProteinHetionet hetionet:covaries:4703-8760Inferred only
NEB covaries with CYB561A3ProteinHetionet hetionet:covaries:220002-4703Inferred only
NEB covaries with DUOXA2ProteinHetionet hetionet:covaries:405753-4703Inferred only
NEB covaries with SERPING1ProteinHetionet hetionet:covaries:4703-710Inferred only
NEB covaries with SLC17A1ProteinHetionet hetionet:covaries:4703-6568Inferred only
NEB covaries with SLC22A8ProteinHetionet hetionet:covaries:4703-9376Inferred only
NEB covaries with SLC2A7ProteinHetionet hetionet:covaries:155184-4703Inferred only
NEB covaries with SLC5A1ProteinHetionet hetionet:covaries:4703-6523Inferred only
NEB covaries with SLC66A3ProteinHetionet hetionet:covaries:130814-4703Inferred only
NEB interacts with ABI1ProteinHetionet hetionet:interacts:10006-4703Inferred only
ACTN4 interacts with NEBProteinHetionet hetionet:interacts:4703-81Inferred only
APC interacts with NEBProteinHetionet hetionet:interacts:324-4703Inferred only

Show the remaining 16

CALM1 interacts with NEBProteinHetionet hetionet:interacts:4703-801Inferred only
CALM1 interacts with NEBProteinHetionet hetionet:interacts:4703-808Inferred only
CALM1 interacts with NEBProteinHetionet hetionet:interacts:4703-805Inferred only
DES interacts with NEBProteinHetionet hetionet:interacts:1674-4703Inferred only
NEB interacts with MYPNProteinHetionet hetionet:interacts:4703-84665Inferred only
NEB interacts with TMOD1ProteinHetionet hetionet:interacts:4703-7111Inferred only
NEB interacts with TMOD4ProteinHetionet hetionet:interacts:29765-4703Inferred only
NEB interacts with TRIM55ProteinHetionet hetionet:interacts:4703-84675Inferred only
NEB interacts with TRIM63ProteinHetionet hetionet:interacts:4703-84676Inferred only
NEB interacts with TTNProteinHetionet hetionet:interacts:4703-7273Inferred only
NEB interacts with UBCProteinHetionet hetionet:interacts:4703-7316Inferred only
NEB participates in Factors and pathways affecting insulin like growth factor IGF1 Akt signalingPathwayWikiPathways WP3850Inferred only
NEB participates in Muscle contractionPathwayReactome R-HSA-397014Inferred only
NEB participates in Striated Muscle ContractionPathwayReactome R-HSA-390522Inferred only
NEB participates in Striated muscle contraction pathwayPathwayWikiPathways WP383Inferred only
NEB regulates regulation of actin filament lengthBiological processgene ontology P20929|GO:0030832Inferred only

Other names

1 name

Resolves to: NEB

Also called: Nebulin

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