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Proteins/UNIPROT:O14594

NCAN

Protein·UNIPROT:O14594

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May modulate neuronal adhesion and neurite growth during development by binding to neural cell adhesion molecules (NG-CAM and N-CAM). Chondroitin sulfate proteoglycan; binds to hyaluronic acid.

Function from UniProtKB (O14594), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

42 statements

42 statements · 3 reference databases · Subject: NCAN · Sources: Hetionet, Reactome, WikiPathways

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CRTC1 covaries with NCANProteinHetionet hetionet:covaries:1463-23373Inferred only
NCAN covaries with FBN3ProteinHetionet hetionet:covaries:1463-84467Inferred only
NCAN covaries with MAN2B1ProteinHetionet hetionet:covaries:1463-4125Inferred only
MYO9B covaries with NCANProteinHetionet hetionet:covaries:1463-4650Inferred only
PCDHB15 covaries with NCANProteinHetionet hetionet:covaries:1463-56121Inferred only
PCDHB2 covaries with NCANProteinHetionet hetionet:covaries:1463-56133Inferred only
NCAN covaries with PDE4CProteinHetionet hetionet:covaries:1463-5143Inferred only
VCAN covaries with NCANProteinHetionet hetionet:covaries:1462-1463Inferred only
NCAN interacts with CNTN2ProteinHetionet hetionet:interacts:1463-6900Inferred only
NCAN interacts with HMGB1ProteinHetionet hetionet:interacts:1463-3146Inferred only
NCAN interacts with L1CAMProteinHetionet hetionet:interacts:1463-3897Inferred only
NCAN interacts with NCAM1ProteinHetionet hetionet:interacts:1463-4684Inferred only

Show the remaining 30

NCAN interacts with PTNProteinHetionet hetionet:interacts:1463-5764Inferred only
NCAN interacts with TNCProteinHetionet hetionet:interacts:1463-3371Inferred only
NCAN interacts with TNRProteinHetionet hetionet:interacts:1463-7143Inferred only
NCAN participates in Axon guidancePathwayReactome R-HSA-422475Inferred only
NCAN participates in Chondroitin sulfate/dermatan sulfate metabolismPathwayReactome R-HSA-1793185Inferred only
NCAN participates in CS-GAG biosynthesisPathwayReactome R-HSA-2022870Inferred only
NCAN participates in CS/DS degradationPathwayReactome R-HSA-2024101Inferred only
NCAN participates in Defective B3GALT6 causes EDSP2 and SEMDJL1PathwayReactome R-HSA-4420332Inferred only
NCAN participates in Defective B3GAT3 causes JDSSDHDPathwayReactome R-HSA-3560801Inferred only
NCAN participates in Defective B4GALT7 causes EDS, progeroid typePathwayReactome R-HSA-3560783Inferred only
NCAN participates in Defective CHST14 causes EDS, musculocontractural typePathwayReactome R-HSA-3595174Inferred only
NCAN participates in Defective CHST3 causes SEDCJDPathwayReactome R-HSA-3595172Inferred only
NCAN participates in Defective CHSY1 causes TPBSPathwayReactome R-HSA-3595177Inferred only
NCAN participates in Developmental BiologyPathwayReactome R-HSA-1266738Inferred only
NCAN participates in DiseasePathwayReactome R-HSA-1643685Inferred only
NCAN participates in Diseases associated with glycosaminoglycan metabolismPathwayReactome R-HSA-3560782Inferred only
NCAN participates in Diseases of glycosylationPathwayReactome R-HSA-3781865Inferred only
NCAN participates in Diseases of metabolismPathwayReactome R-HSA-5668914Inferred only
NCAN participates in DS-GAG biosynthesisPathwayReactome R-HSA-2022923Inferred only
NCAN participates in ECM proteoglycansPathwayReactome R-HSA-3000178Inferred only
NCAN participates in Extracellular matrix organizationPathwayReactome R-HSA-1474244Inferred only
NCAN participates in Glycosaminoglycan metabolismPathwayReactome R-HSA-1630316Inferred only
NCAN participates in Glycosaminoglycan-protein linkage region biosynthesisPathwayReactome R-HSA-1971475Inferred only
NCAN participates in L1CAM interactionsPathwayReactome R-HSA-373760Inferred only
NCAN participates in MetabolismPathwayReactome R-HSA-1430728Inferred only
NCAN participates in Metabolism of carbohydrates and carbohydrate derivativesPathwayReactome R-HSA-71387Inferred only
NCAN participates in NCAM signaling for neurite out-growthPathwayReactome R-HSA-375165Inferred only
NCAN participates in NCAM1 interactionsPathwayReactome R-HSA-419037Inferred only
NCAN participates in Nervous system developmentPathwayReactome R-HSA-9675108Inferred only
NCAN participates in Spinal cord injuryPathwayWikiPathways WP2431Inferred only

Other names

4 names

Resolves to: NCAN

Also called: Chondroitin sulfate proteoglycan 3CSPG3NEURNeurocan core protein

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