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Proteins/UNIPROT:Q147X3
Catalytic subunit of the N-terminal acetyltransferase C (NatC) complex. Catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Leu-Ala and Met-Leu-Gly. N-terminal acetylation protects proteins from ubiquitination and degradation by the N-end rule pathway. Necessary for the lysosomal localization and function of ARL8B sugeesting that ARL8B is a NatC substrate..
Function from UniProtKB (Q147X3), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
10 statements
10 statements · 4 reference databases · Subject: NAA30 · Sources: Bgee, Hetionet, Reactome, WikiPathways
5 reactions
N-terminal L-methionyl-L-leucyl-[protein]+acetyl-CoAN-terminal N(alpha)-acetyl-L-methionyl-L-leucyl-[protein]+coenzyme A(4-)+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:50520CC BY 4.0Reference data
N-terminal L-methionyl-L-isoleucyl-[protein]+acetyl-CoAN-terminal N(alpha)-acetyl-L-methionyl-L-isoleucyl-[protein]+coenzyme A(4-)+hydron
Catalysed by
6 names
Resolves to: NAA30
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:50524CC BY 4.0Reference data
N-terminal L-methionyl-L-phenylalanyl-[protein]+acetyl-CoAN-terminal N(alpha)-acetyl-L-methionyl-L-phenylalanyl-[protein]+coenzyme A(4-)+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:50528CC BY 4.0Reference data
N-terminal L-methionyl-L-tyrosyl-[protein]+acetyl-CoAN-terminal N(alpha)-acetyl-L-methionyl-L-tyrosyl-[protein]+coenzyme A(4-)+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:50532CC BY 4.0Reference data
N-terminal L-methionyl-L-tryptophyl-[protein]+acetyl-CoAN-terminal N(alpha)-acetyl-L-methionyl-L-tryptophyl-[protein]+coenzyme A(4-)+hydron
Catalysed by NAA30
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:50560CC BY 4.0Reference data