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Proteins/UNIPROT:Q9NWN3
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex promoting ubiquitination and proteasomal degradation of specific target proteins including HNRNPU. Regulates both the G2/M transition and anaphase entry in meiotic oocytes (By similarity)..
(Microbial infection) Plays a positive role in latent HIV-1 activation. Mechanistically, promotes hnRNP U/HNRNPU ubiquitination, which leads to its degradation and abolishment of the interaction between hnRNP U and HIV-1 Rev mRNA..
Function from UniProtKB (Q9NWN3), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
14 statements
14 statements · 1 reference database · Subject: FBXO34 · Sources: Hetionet
2 names
Resolves to: FBXO34