Proteins/UNIPROT:Q00872

MYBPC1

ProteinUNIPROT:Q00872

Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. Slow skeletal protein that binds to both myosin and actin. In vitro, binds to native thin filaments and modifies the activity of actin-activated myosin ATPase. May modulate muscle contraction or may play a more structural role..

Function from UniProtKB (Q00872), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

7 rows

arthrogryposis has a germline basis in MYBPC1DiseaseGenCC HGNC:7549|MONDO:0008779Inferred only
arthrogryposis, distal, type 1B has a germline basis in MYBPC1DiseaseGenCC HGNC:7549|MONDO:0013698Inferred only
digitotalar dysmorphism has a germline basis in MYBPC1DiseaseGenCC HGNC:7549|MONDO:0015240Inferred only
lethal congenital contracture syndrome 3 has a germline basis in MYBPC1DiseaseGenCC HGNC:7549|MONDO:0012656Inferred only
lethal congenital contracture syndrome 4 has a germline basis in MYBPC1DiseaseGenCC HGNC:7549|MONDO:0013965Inferred only
myopathy has a germline basis in MYBPC1DiseaseGenCC HGNC:7549|MONDO:0005336Inferred only
myopathy, congenital, with tremor has a germline basis in MYBPC1DiseaseGenCC HGNC:7549|MONDO:0032797Inferred only

Statements

26 statements

26 statements · 3 reference databases · Subject: MYBPC1 · Sources: Hetionet, Reactome, WikiPathways

Order

MYBPC1 covaries with MYH1ProteinHetionet hetionet:covaries:4604-4619Inferred only
MYBPC1 covaries with MYH2ProteinHetionet hetionet:covaries:4604-4620Inferred only
ACO1 interacts with MYBPC1ProteinHetionet hetionet:interacts:4604-48Inferred only
MYBPC1 interacts with AMOTProteinHetionet hetionet:interacts:154796-4604Inferred only
MYBPC1 interacts with ANKRD1ProteinHetionet hetionet:interacts:27063-4604Inferred only
MYBPC1 interacts with ASH2LProteinHetionet hetionet:interacts:4604-9070Inferred only
MYBPC1 interacts with C1QTNF9ProteinHetionet hetionet:interacts:338872-4604Inferred only
CALM1 interacts with MYBPC1ProteinHetionet hetionet:interacts:4604-808Inferred only
CALM1 interacts with MYBPC1ProteinHetionet hetionet:interacts:4604-801Inferred only
CALM1 interacts with MYBPC1ProteinHetionet hetionet:interacts:4604-805Inferred only
CAPN3 interacts with MYBPC1ProteinHetionet hetionet:interacts:4604-825Inferred only
MYBPC1 interacts with CLIP4ProteinHetionet hetionet:interacts:4604-79745Inferred only

Show the remaining 14

MYBPC1 interacts with DNAJB5ProteinHetionet hetionet:interacts:25822-4604Inferred only
MYBPC1 interacts with DNAJB6ProteinHetionet hetionet:interacts:10049-4604Inferred only
MYBPC1 interacts with DYSFProteinHetionet hetionet:interacts:4604-8291Inferred only
FHL1 interacts with MYBPC1ProteinHetionet hetionet:interacts:2273-4604Inferred only
MYBPC1 interacts with KLHL41ProteinHetionet hetionet:interacts:10324-4604Inferred only
MYBPC1 interacts with KYProteinHetionet hetionet:interacts:339855-4604Inferred only
MEOX2 interacts with MYBPC1ProteinHetionet hetionet:interacts:4223-4604Inferred only
MYBPC1 interacts with MYBPC2ProteinHetionet hetionet:interacts:4604-4606Inferred only
MYBPC1 interacts with NCF1ProteinHetionet hetionet:interacts:4604-653361Inferred only
MYBPC1 interacts with TTNProteinHetionet hetionet:interacts:4604-7273Inferred only
MYBPC1 interacts with USP25ProteinHetionet hetionet:interacts:29761-4604Inferred only
MYBPC1 participates in Muscle contractionPathwayReactome R-HSA-397014Inferred only
MYBPC1 participates in Striated Muscle ContractionPathwayReactome R-HSA-390522Inferred only
MYBPC1 participates in Striated muscle contraction pathwayPathwayWikiPathways WP383Inferred only

Other names

3 names

Resolves to: MYBPC1

Also called: C-protein, skeletal muscle slow isoformMYBPCSSlow MyBP-C

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