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Proteins/UNIPROT:Q5TKA1

LIN9

Protein·UNIPROT:Q5TKA1

Open in the graph

Acts as a tumor suppressor. Inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expression of genes required for the G1/S transition..

Function from UniProtKB (Q5TKA1), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

26 statements

26 statements · 4 reference databases · Subject: LIN9 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

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LRRIQ1 covaries with LIN9ProteinHetionet hetionet:covaries:286826-84125Inferred only
MYBL2 interacts with LIN9ProteinHetionet hetionet:interacts:286826-4605Inferred only
RB1 interacts with LIN9ProteinHetionet hetionet:interacts:286826-5925Inferred only
RBBP4 interacts with LIN9ProteinHetionet hetionet:interacts:286826-5928Inferred only
UBC interacts with LIN9ProteinHetionet hetionet:interacts:286826-7316Inferred only
LIN9 participates in Cell CyclePathwayReactome R-HSA-1640170Inferred only
LIN9 participates in Cell Cycle, MitoticPathwayReactome R-HSA-69278Inferred only
LIN9 participates in Cyclin A:Cdk2-associated events at S phase entryPathwayReactome R-HSA-69656Inferred only
LIN9 participates in Cyclin E associated events during G1/S transitionPathwayReactome R-HSA-69202Inferred only
LIN9 participates in DYRK1A involvement regarding cell proliferation in brain developmentPathwayWikiPathways WP5180Inferred only
LIN9 participates in G0 and Early G1PathwayReactome R-HSA-1538133Inferred only
LIN9 participates in G1/S TransitionPathwayReactome R-HSA-69206Inferred only

Show the remaining 14

LIN9 participates in G1/S-Specific TranscriptionPathwayReactome R-HSA-69205Inferred only
LIN9 participates in G2/M TransitionPathwayReactome R-HSA-69275Inferred only
LIN9 participates in Gastric cancer network 1PathwayWikiPathways WP2361Inferred only
LIN9 participates in Mitotic G1 phase and G1/S transitionPathwayReactome R-HSA-453279Inferred only
LIN9 participates in Mitotic G2-G2/M phasesPathwayReactome R-HSA-453274Inferred only
LIN9 participates in Polo-like kinase mediated eventsPathwayReactome R-HSA-156711Inferred only
LIN9 participates in S PhasePathwayReactome R-HSA-69242Inferred only
LIN9 participates in Transcription of E2F targets under negative control by DREAM complexPathwayReactome R-HSA-1362277Inferred only
LIN9 participates in Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1PathwayReactome R-HSA-1362300Inferred only
LIN9 regulates negative regulation of DNA-templated transcriptionBiological processgene ontology Q5TKA1|GO:0045892Inferred only
LIN9 regulates positive regulation of transcription by RNA polymerase IIBiological processgene ontology Q5TKA1|GO:0045944Inferred only
LIN9 regulates regulation of cell cycleBiological processgene ontology Q5TKA1|GO:0051726Inferred only
LIN9 regulates regulation of DNA-templated transcriptionBiological processgene ontology Q5TKA1|GO:0006355Inferred only
LIN9 regulates regulation of transcription by RNA polymerase IIBiological processgene ontology Q5TKA1|GO:0006357Inferred only

Other names

8 names

Resolves to: LIN9

Also called: BARABeta subunit-associated regulator of apoptosishLin-9HuLin-9pRB-associated proteinTGSTUDOR gene similar proteinType I interferon receptor beta chain-associated protein

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