Pathway
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
In G0 and early G1, expression of E2F target genes such as Cyclin A, E2F1, CDC2 and MYBL2 is inhibited by complexes containing p130 (RBL2) and p107 (RBL1), respectively, and histone deacetylase HDAC1.
REACT:R-HSA-1362300Reactome
What the reference databases state
Statements
16 statements
16 statements · 1 reference database · Subject: Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 · Sources: Reactome
- CCNA2 participates in Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1ProteinReactome R-HSA-1362300Inferred only
- CDK1 participates in Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1ProteinReactome R-HSA-1362300Inferred only
- E2F1 participates in Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1ProteinReactome R-HSA-1362300Inferred only
- E2F4 participates in Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1ProteinReactome R-HSA-1362300Inferred only
- E2F5 participates in Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1ProteinReactome R-HSA-1362300Inferred only
- HDAC1 participates in Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1ProteinReactome R-HSA-1362300Inferred only
- LIN37 participates in Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1ProteinReactome R-HSA-1362300Inferred only
- LIN52 participates in Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1ProteinReactome R-HSA-1362300Inferred only
- LIN54 participates in Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1ProteinReactome R-HSA-1362300Inferred only
- LIN9 participates in Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1ProteinReactome R-HSA-1362300Inferred only
- MYBL2 participates in Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1ProteinReactome R-HSA-1362300Inferred only
- RBBP4 participates in Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1ProteinReactome R-HSA-1362300Inferred only
Show the remaining 4
- RBL1 participates in Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1ProteinReactome R-HSA-1362300Inferred only
- RBL2 participates in Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1ProteinReactome R-HSA-1362300Inferred only
- TFDP1 participates in Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1ProteinReactome R-HSA-1362300Inferred only
- TFDP2 participates in Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1ProteinReactome R-HSA-1362300Inferred only