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Proteins/UNIPROT:Q9Y366

IFT52

Protein·UNIPROT:Q9Y366

Open in the graph

Involved in ciliogenesis as part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia. Required for the anterograde transport of IFT88..

Function from UniProtKB (Q9Y366), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

2 rows

cranioectodermal dysplasia has a germline basis in IFT52DiseaseGenCC HGNC:15901|MONDO:0009032Inferred only
short-rib thoracic dysplasia 16 with or without polydactyly has a germline basis in IFT52DiseaseGenCC HGNC:15901|MONDO:0014915Inferred only

Statements

21 statements

21 statements · 3 reference databases · Subject: IFT52 · Sources: Hetionet, Reactome, WikiPathways

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UBC interacts with IFT52ProteinHetionet hetionet:interacts:51098-7316Inferred only
UBD interacts with IFT52ProteinHetionet hetionet:interacts:10537-51098Inferred only
IFT52 participates in Assembly of the 9+0 primary ciliumPathwayReactome R-HSA-9975921Inferred only
IFT52 participates in Bardet Biedl syndromePathwayWikiPathways WP5234Inferred only
IFT52 participates in Ciliary landscapePathwayWikiPathways WP4352Inferred only
IFT52 participates in CiliopathiesPathwayWikiPathways WP4803Inferred only
IFT52 participates in Cilium AssemblyPathwayReactome R-HSA-5617833Inferred only
IFT52 participates in Genes related to primary cilium development based on CRISPR PathwayWikiPathways WP4536Inferred only
IFT52 participates in Hedgehog 'off' statePathwayReactome R-HSA-5610787Inferred only
IFT52 participates in Intraflagellar transportPathwayReactome R-HSA-5620924Inferred only
IFT52 participates in Organelle biogenesis and maintenancePathwayReactome R-HSA-1852241Inferred only
IFT52 participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only

Show the remaining 9

IFT52 participates in Signaling by HedgehogPathwayReactome R-HSA-5358351Inferred only
IFT52 participates in Smith Magenis and Potocki Lupski syndrome copy number variationPathwayWikiPathways WP5381Inferred only
C2CD2 decreases the expression of IFT52ProteinHetionet hetionet:regulates:25966-51098Inferred only
GTF2E2 decreases the expression of IFT52ProteinHetionet hetionet:regulates:2961-51098Inferred only
KMT2A decreases the expression of IFT52ProteinHetionet hetionet:regulates:4297-51098Inferred only
LDHB decreases the expression of IFT52ProteinHetionet hetionet:regulates:3945-51098Inferred only
MAP2K2 decreases the expression of IFT52ProteinHetionet hetionet:regulates:5605-51098Inferred only
RXYLT1 decreases the expression of IFT52ProteinHetionet hetionet:regulates:10329-51098Inferred only
TIMP1 decreases the expression of IFT52ProteinHetionet hetionet:regulates:7076-51098Inferred only

Other names

5 names

Resolves to: IFT52

Also called: C20orf9Intraflagellar transport protein 52 homologNGD5NGD5 homologProtein NGD5 homolog

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