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Proteins/UNIPROT:P00739
Primate-specific plasma protein associated with apolipoprotein L-I (apoL-I)-containing high-density lipoprotein (HDL). This HDL particle, termed trypanosome lytic factor-1 (TLF-1), mediates human innate immune protection against many species of African trypanosomes. Binds hemoglobin with high affinity and may contribute to the clearance of cell-free hemoglobin to allow hepatic recycling of heme iron..
Function from UniProtKB (P00739), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
5 statements
5 statements · 2 reference databases · Subject: HPR · Sources: Hetionet, Reactome
1 name
Resolves to: HPR