Proteins/UNIPROT:Q13823

GNL2

ProteinUNIPROT:Q13823

GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels..

Function from UniProtKB (Q13823), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

28 statements

28 statements · 1 reference database · Subject: GNL2 · Sources: Hetionet

Order

APP interacts with GNL2ProteinHetionet hetionet:interacts:29889-351Inferred only
GNL2 interacts with CAND1ProteinHetionet hetionet:interacts:29889-55832Inferred only
ESR1 interacts with GNL2ProteinHetionet hetionet:interacts:2099-29889Inferred only
FOS interacts with GNL2ProteinHetionet hetionet:interacts:2353-29889Inferred only
GNL2 interacts with MMS19ProteinHetionet hetionet:interacts:29889-64210Inferred only
GNL2 interacts with SIRT7ProteinHetionet hetionet:interacts:29889-51547Inferred only
SUMO2 interacts with GNL2ProteinHetionet hetionet:interacts:29889-6613Inferred only
UBC interacts with GNL2ProteinHetionet hetionet:interacts:29889-7316Inferred only
ARG1 increases the expression of GNL2ProteinHetionet hetionet:regulates:383-29889Inferred only
BPHL increases the expression of GNL2ProteinHetionet hetionet:regulates:670-29889Inferred only
CD320 decreases the expression of GNL2ProteinHetionet hetionet:regulates:51293-29889Inferred only
COPB2 increases the expression of GNL2ProteinHetionet hetionet:regulates:9276-29889Inferred only

Show the remaining 16

CPE decreases the expression of GNL2ProteinHetionet hetionet:regulates:1363-29889Inferred only
FBXO7 increases the expression of GNL2ProteinHetionet hetionet:regulates:25793-29889Inferred only
HDAC6 decreases the expression of GNL2ProteinHetionet hetionet:regulates:10013-29889Inferred only
HSF1 decreases the expression of GNL2ProteinHetionet hetionet:regulates:3297-29889Inferred only
IGF2R increases the expression of GNL2ProteinHetionet hetionet:regulates:3482-29889Inferred only
MYCBP decreases the expression of GNL2ProteinHetionet hetionet:regulates:26292-29889Inferred only
PABPC1 increases the expression of GNL2ProteinHetionet hetionet:regulates:26986-29889Inferred only
PHF23 decreases the expression of GNL2ProteinHetionet hetionet:regulates:79142-29889Inferred only
POLR2A increases the expression of GNL2ProteinHetionet hetionet:regulates:5430-29889Inferred only
POLR2I increases the expression of GNL2ProteinHetionet hetionet:regulates:5438-29889Inferred only
PRPF6 increases the expression of GNL2ProteinHetionet hetionet:regulates:24148-29889Inferred only
SAP18 increases the expression of GNL2ProteinHetionet hetionet:regulates:10284-29889Inferred only
TBC1D31 increases the expression of GNL2ProteinHetionet hetionet:regulates:93594-29889Inferred only
TRIM13 increases the expression of GNL2ProteinHetionet hetionet:regulates:10206-29889Inferred only
TRIP13 increases the expression of GNL2ProteinHetionet hetionet:regulates:9319-29889Inferred only
UBA52 increases the expression of GNL2ProteinHetionet hetionet:regulates:7311-29889Inferred only

Other names

3 names

Resolves to: GNL2

Also called: Autoantigen NGP-1NGP1Nucleolar GTP-binding protein 2

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