Proteins/UNIPROT:O94915

FRYL

ProteinUNIPROT:O94915

Plays a key role in maintaining the integrity of polarized cell extensions during morphogenesis, regulates the actin cytoskeleton and plays a key role in patterning sensory neuron dendritic fields by promoting avoidance between homologous dendrites as well as by limiting dendritic branching (By similarity). May function as a transcriptional activator..

Function from UniProtKB (O94915), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

2 rows

complex neurodevelopmental disorder has a germline basis in FRYLDiseaseGenCC HGNC:29127|MONDO:0100038Inferred only
Pan-Chung-Bellen syndrome has a germline basis in FRYLDiseaseGenCC HGNC:29127|MONDO:0975953Inferred only

Statements

22 statements

22 statements · 1 reference database · Subject: FRYL · Sources: Hetionet

Order

FRYL covaries with DCDProteinHetionet hetionet:covaries:117159-285527Inferred only
ABCF1 interacts with FRYLProteinHetionet hetionet:interacts:23-285527Inferred only
DISC1 interacts with FRYLProteinHetionet hetionet:interacts:27185-285527Inferred only
GRK5 interacts with FRYLProteinHetionet hetionet:interacts:285527-2869Inferred only
HOMER3 interacts with FRYLProteinHetionet hetionet:interacts:285527-9454Inferred only
MMS19 interacts with FRYLProteinHetionet hetionet:interacts:285527-64210Inferred only
PELI2 interacts with FRYLProteinHetionet hetionet:interacts:285527-57161Inferred only
SIRT7 interacts with FRYLProteinHetionet hetionet:interacts:285527-51547Inferred only
UBC interacts with FRYLProteinHetionet hetionet:interacts:285527-7316Inferred only
YWHAG interacts with FRYLProteinHetionet hetionet:interacts:285527-7532Inferred only
AURKA increases the expression of FRYLProteinHetionet hetionet:regulates:6790-285527Inferred only
DDR1 increases the expression of FRYLProteinHetionet hetionet:regulates:780-285527Inferred only

Show the remaining 10

ECD decreases the expression of FRYLProteinHetionet hetionet:regulates:11319-285527Inferred only
KNDC1 increases the expression of FRYLProteinHetionet hetionet:regulates:85442-285527Inferred only
MSH6 increases the expression of FRYLProteinHetionet hetionet:regulates:2956-285527Inferred only
MTOR increases the expression of FRYLProteinHetionet hetionet:regulates:2475-285527Inferred only
PNPO increases the expression of FRYLProteinHetionet hetionet:regulates:55163-285527Inferred only
RPS14 increases the expression of FRYLProteinHetionet hetionet:regulates:6208-285527Inferred only
RPS27A increases the expression of FRYLProteinHetionet hetionet:regulates:6233-285527Inferred only
RUVBL1 increases the expression of FRYLProteinHetionet hetionet:regulates:8607-285527Inferred only
SRPRB increases the expression of FRYLProteinHetionet hetionet:regulates:58477-285527Inferred only
TOLLIP increases the expression of FRYLProteinHetionet hetionet:regulates:54472-285527Inferred only

Other names

5 names

Resolves to: FRYL

Also called: AF4P12ALL1-fused gene from chromosome 4p12 proteinfurry homolog-likeKIAA0826Protein furry homolog-like

← Every protein Find it in the graph →