Proteins/UNIPROT:Q8TAT2

FGFBP3

ProteinUNIPROT:Q8TAT2

Heparin-binding protein which binds to FGF2, prevents binding of FGF2 to heparin and probably inhibits immobilization of FGF2 on extracellular matrix glycosaminoglycans, allowing its release and subsequent activation of FGFR signaling which leads to increased vascular permeability..

Function from UniProtKB (Q8TAT2), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

11 statements

11 statements · 3 reference databases · Subject: FGFBP3 · Sources: gene ontology, Hetionet, Reactome

Order

APBA3 covaries with FGFBP3ProteinHetionet hetionet:covaries:143282-9546Inferred only
MAP2K2 covaries with FGFBP3ProteinHetionet hetionet:covaries:143282-5605Inferred only
NEK3 covaries with FGFBP3ProteinHetionet hetionet:covaries:143282-4752Inferred only
FGFBP3 participates in FGFR2 ligand binding and activationPathwayReactome R-HSA-190241Inferred only
FGFBP3 participates in FGFR2b ligand binding and activationPathwayReactome R-HSA-190377Inferred only
FGFBP3 participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
FGFBP3 participates in Signaling by FGFRPathwayReactome R-HSA-190236Inferred only
FGFBP3 participates in Signaling by FGFR2PathwayReactome R-HSA-5654738Inferred only
FGFBP3 participates in Signaling by Receptor Tyrosine KinasesPathwayReactome R-HSA-9006934Inferred only
FGFBP3 regulates positive regulation of fibroblast growth factor receptor signaling pathwayBiological processgene ontology Q8TAT2|GO:0045743Inferred only
FGFBP3 regulates positive regulation of vascular permeabilityBiological processgene ontology Q8TAT2|GO:0043117Inferred only

Other names

4 names

Resolves to: FGFBP3

Also called: C10orf13FGF-binding protein 3FGF-BP3FGFBP-3

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