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A reference for what the literature reports. Not medical advice.

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Proteins/UNIPROT:Q9UKT8

FBXW2

Protein·UNIPROT:Q9UKT8

Open in the graph

Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

Function from UniProtKB (Q9UKT8), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

27 statements

27 statements · 4 reference databases · Subject: FBXW2 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

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FBXW2 covaries with H2BC4; H2BC6; H2BC7; H2BC8; H2BC10ProteinHetionet hetionet:covaries:26190-8339Inferred only
FBXW2 covaries with H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12ProteinHetionet hetionet:covaries:26190-8351Inferred only
FBXW2 covaries with PTMAProteinHetionet hetionet:covaries:26190-5757Inferred only
FBXW2 covaries with RPL9; RPL9P7; RPL9P8; RPL9P9ProteinHetionet hetionet:covaries:26190-6133Inferred only
FBXW2 covaries with SIAH1ProteinHetionet hetionet:covaries:26190-6477Inferred only
FBXW2 covaries with TMEM238ProteinHetionet hetionet:covaries:26190-388564Inferred only
ZFP36L1 covaries with FBXW2ProteinHetionet hetionet:covaries:26190-677Inferred only
CDC34 interacts with FBXW2ProteinHetionet hetionet:interacts:26190-997Inferred only
CUL1 interacts with FBXW2ProteinHetionet hetionet:interacts:26190-8454Inferred only
GCM1 interacts with FBXW2ProteinHetionet hetionet:interacts:26190-8521Inferred only
HSP90AA1 interacts with FBXW2ProteinHetionet hetionet:interacts:26190-3320Inferred only
MYB interacts with FBXW2ProteinHetionet hetionet:interacts:26190-4602Inferred only

Show the remaining 15

REST interacts with FBXW2ProteinHetionet hetionet:interacts:26190-5978Inferred only
SKP1 interacts with FBXW2ProteinHetionet hetionet:interacts:26190-6500Inferred only
UBE2D2 interacts with FBXW2ProteinHetionet hetionet:interacts:26190-7322Inferred only
FBXW2 participates in Adaptive Immune SystemPathwayReactome R-HSA-1280218Inferred only
FBXW2 participates in Antigen processing: Ubiquitination & Proteasome degradationPathwayReactome R-HSA-983168Inferred only
FBXW2 participates in Association of TriC/CCT with target proteins during biosynthesisPathwayReactome R-HSA-390471Inferred only
FBXW2 participates in Chaperonin-mediated protein foldingPathwayReactome R-HSA-390466Inferred only
FBXW2 participates in Class I MHC mediated antigen processing & presentationPathwayReactome R-HSA-983169Inferred only
FBXW2 participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
FBXW2 participates in Metabolism of proteinsPathwayReactome R-HSA-392499Inferred only
FBXW2 participates in NeddylationPathwayReactome R-HSA-8951664Inferred only
FBXW2 participates in Post-translational protein modificationPathwayReactome R-HSA-597592Inferred only
FBXW2 participates in Protein foldingPathwayReactome R-HSA-391251Inferred only
FBXW2 participates in Wnt signaling and pluripotencyPathwayWikiPathways WP399Inferred only
FBXW2 regulates regulation of cell cycle processBiological processgene ontology Q9UKT8|GO:0010564Inferred only

Other names

5 names

Resolves to: FBXW2

Also called: F-box and WD-40 domain-containing protein 2FBW2FWD2MD6Protein MD6

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